Vitamin B1 (Thiamine) Market Size & Share Trends, 2033

Vitamin B1 (Thiamine) Market Overview

The Vitamin B1 (Thiamine) Market size was valued at USD 788.17 million in 2024 and is expected to reach USD 1199.63 million by 2033, growing at a CAGR of 4.7XX% from 2025 to 2033.

The global Vitamin B1 (Thiamine) Market is expanding significantly due to its growing applications in the food, feed, and pharmaceutical industries. Thiamine, a water-soluble B-vitamin, plays a critical role in carbohydrate metabolism and neurological functions. It is widely used as a dietary supplement and is often incorporated into fortified food products, livestock feed, and pharmaceutical formulations. In 2023, the global demand for Vitamin B1 exceeded 18,000 metric tons, with over 40% of that volume utilized in the pharmaceutical sector.

The food and beverage industry accounted for approximately 6,800 metric tons of Vitamin B1 usage in 2023, while the animal feed industry consumed over 5,000 metric tons. The pharmaceutical-grade segment has witnessed a sharp rise in production, with China producing more than 7,200 metric tons of pharmaceutical-grade thiamine in 2023 alone. The U.S., Germany, China, and India are leading consumers of Vitamin B1 due to strong dietary supplementation programs and industrial applications.

Key Findings

DRIVER: Increasing use of Vitamin B1 in pharmaceutical and dietary supplement formulations.

COUNTRY/REGION: China dominates global production and export of Vitamin B1, particularly in pharmaceutical grade.

SEGMENT: Pharmaceutical grade Vitamin B1 leads the market in both volume and demand.

Vitamin B1 (Thiamine) Market Trends

The Vitamin B1 Market is witnessing multiple dynamic shifts aligned with consumer wellness, functional food development, and livestock health improvements. One major trend is the expansion of vitamin fortification in packaged food products. In 2023, over 10,500 packaged food and beverage products globally listed Vitamin B1 among their top five nutritional additives. This includes products such as energy drinks, cereals, and infant formula.

In pharmaceuticals, over 2,800 new over-the-counter and prescription drugs were launched globally in 2023 containing thiamine as a core active ingredient, particularly in multivitamin and neurological support categories. Demand is rising for combination therapies involving thiamine and other B-complex vitamins to address deficiency disorders and metabolic syndromes.

Vitamin B1 (Thiamine) Market Dynamics

The Vitamin B1 (Thiamine) market is experiencing robust growth, propelled by increasing health consciousness, the rising prevalence of chronic diseases, and a global shift toward preventive healthcare. Valued at approximately USD 1.51 billion in 2025, the market is projected to reach USD 2.21 billion by 2029, reflecting a compound annual growth rate (CAGR) of 10% . This expansion is largely driven by heightened demand for dietary supplements, as consumers seek to bolster immune function, enhance energy metabolism, and support nervous system health.

Pharmaceutical applications are also contributing significantly to market dynamics, with innovations such as intravenous thiamine infusions offering effective solutions for individuals with absorption challenges or severe deficiencies . Additionally, the food and beverage industry is increasingly incorporating thiamine into fortified products, catering to consumers' growing preference for functional foods. In the animal feed sector, thiamine supplementation is recognized for promoting livestock health and productivity.

DRIVER

Rising demand for pharmaceuticals and nutritional supplements

Vitamin B1 is extensively used in treating conditions like beriberi, Wernicke’s encephalopathy, and other neurological disorders. In 2023, over 80 million prescriptions globally included thiamine-based supplements or medications. Hospitals and health systems across Europe and North America reported using more than 2,300 metric tons of pharmaceutical-grade Vitamin B1 for patient treatments. Its inclusion in prenatal vitamins and immune support products also contributes to robust growth.

RESTRAINT

Raw material supply volatility

The production of synthetic thiamine involves intermediates like aniline and hydroxylamine hydrochloride, which are susceptible to price volatility due to upstream supply chain challenges. In 2023, raw material shortages in Asia led to a 14% increase in thiamine production costs in Q2. Additionally, environmental restrictions in China caused temporary shutdowns of two major facilities in Hebei and Anhui provinces, impacting the availability of feed- and pharma-grade thiamine globally.

OPPORTUNITY

Growth in functional food and biofortification programs

Government-led fortification programs in Southeast Asia and sub-Saharan Africa are generating new opportunities for Vitamin B1 suppliers. In 2023, India’s Food Safety Authority mandated thiamine fortification in wheat flour across 12 states, covering more than 110 million people. Similarly, Bangladesh's public nutrition initiative distributed over 6,000 metric tons of Vitamin B1-enriched food aid. Functional beverages and energy shots also represent an emerging area, with over 750 new SKUs launched globally in 2023.

CHALLENGE

Regulatory complexity and standardization

Disparate regulatory frameworks regarding Vitamin B1 concentration limits and labeling standards across markets complicate global trade. For instance, the European Union restricts pharmaceutical Vitamin B1 dosage per tablet to 100 mg, while the U.S. allows over-the-counter products with up to 500 mg per dose. In 2023, nine Vitamin B1 supplement products were recalled in South America due to labeling inconsistencies, resulting in delayed market entry and reputational risks for manufacturers.

Vitamin B1 (Thiamine) Market Segmentation

The segmentation of the Vitamin B1 (Thiamine) market offers a detailed understanding of the diverse demand patterns and usage across various industries. This market is primarily segmented based on grade, application, and end-use industries. Grade-wise, it includes pharmaceutical grade, food grade, and feed grade thiamine, each tailored to meet specific regulatory and quality standards. Application-based segmentation reveals its utilization in dietary supplements, pharmaceuticals, fortified food products, and animal nutrition. The end-use segmentation further distinguishes the demand among sectors such as the food industry, pharmaceutical manufacturers, and livestock feed producers. This multi-tiered segmentation helps market participants align their strategies with precise consumer needs and regulatory requirements, thereby enhancing supply chain efficiency and targeted product development.

By Type

Food-grade thiamine is primarily used in fortifying processed foods like cereals, flour, and baked goods. In 2023, approximately 6,800 metric tons were consumed globally in food processing. China, the U.S., and France are leading consumers, with fortified foods accounting for 30% of bakery sector output in these regions.
Feed-grade thiamine is used in livestock, particularly in poultry and swine feed formulations. Around 5,000 metric tons were utilized in 2023, with Brazil and India jointly consuming over 2,200 metric tons. It enhances metabolism and improves feed conversion rates in commercial animal husbandry.
This segment dominated 2023 consumption at over 7,200 metric tons. It is used in injectable and oral drug formulations. Hospitals in Germany, the U.S., and Japan alone consumed over 1,100 metric tons of pharma-grade Vitamin B1 in the past year for treating deficiency-related conditions.

By Application

The food industry’s demand is anchored in preventative healthcare. Over 11,000 brands globally included thiamine fortification in their food SKUs in 2023. Breakfast cereals accounted for 33% of total food-based thiamine use, followed by flour and infant formula.
The pharmaceutical industry used over 40% of total global Vitamin B1 production in 2023. Thiamine is used in treatments for alcoholism-induced deficiencies, cardiovascular support, and metabolic disorders. Over 5,000 new branded drugs containing thiamine were registered in 2023 globally.

Regional Outlook For Vitamin B1 (Thiamine) Market

The regional outlook for the Vitamin B1 (Thiamine) market reveals diverse growth patterns influenced by regional health trends, industrial capabilities, and consumer awareness. Asia-Pacific stands as the largest and fastest-growing market, driven by robust production infrastructure in countries like China and India, increasing health consciousness, and rising demand for fortified foods and dietary supplements. North America follows, with significant growth attributed to the expanding nutraceutical and pharmaceutical sectors, alongside heightened consumer focus on preventive healthcare. Europe maintains a steady growth trajectory, supported by stringent regulations promoting food fortification and a strong emphasis on wellness. The Middle East & Africa is also witnessing gradual growth, propelled by improving healthcare infrastructure and increasing awareness of nutritional deficiencies. These regional dynamics underscore the global expansion of the Vitamin B1 market, shaped by localized demands and health priorities.

North America

North America maintains consistent demand driven by its health supplement and fortified food markets. The U.S. consumed over 4,200 metric tons of Vitamin B1 in 2023, while Canada accounted for approximately 610 metric tons. Over 60% of the U.S. thiamine volume is consumed in dietary supplements.

Europe

Europe emphasizes food-grade and pharmaceutical-grade thiamine. Germany, France, and the UK together accounted for over 3,800 metric tons in 2023. Europe also leads in the development of fermentation-based thiamine for sustainable production, with over 8 pilot plants in operation.

Asia-Pacific

Asia-Pacific leads global production with over 10,000 metric tons manufactured in 2023. China is the largest producer, followed by India. Regional demand in Japan and South Korea is expanding in the pharmaceutical and infant nutrition segments. South Korea alone used over 450 metric tons in clinical nutrition formulations.

Middle East & Africa

Middle East & Africa are emerging regions, with combined consumption exceeding 1,200 metric tons in 2023. South Africa and the UAE accounted for over 55% of this volume, driven by government food fortification programs and rising urban supplement consumption.

List of Top Vitamin B1 (Thiamine) Companies

DSM
BASF
Huazhong Pharmaceutical
Brother Enterprises
Tianxin Pharmaceutical
Tianjin Golden World Group
Xinfa Pharmaceutical

DSM: In 2023, DSM produced over 3,000 metric tons of pharmaceutical and food-grade Vitamin B1, covering more than 60 countries through its global distribution channels.

Huazhong Pharmaceutical: One of the largest producers in Asia, Huazhong supplied over 2,500 metric tons globally in 2023, with a strong presence in feed and pharma-grade markets across India, China, and Southeast Asia.

Investment Analysis And Opportunities

The Vitamin B1 Market is seeing increased investments in manufacturing expansion, green production technologies, and end-use innovation. In 2023, DSM invested $38 million in retrofitting its European Vitamin B1 facility to support clean production using renewable feedstocks, cutting carbon emissions by 22%.

Chinese companies are ramping up capacity to meet export demand. Xinfa Pharmaceutical added 8,000 square meters to its Vitamin B1 manufacturing plant in 2023, increasing annual output by 1,200 metric tons. India is also attracting investment, with Brother Enterprises entering a JV with a local producer to establish a 3,500 metric ton/year capacity facility near Hyderabad.

In the EU, investment opportunities exist in fermentation-derived thiamine. BASF and two biotech start-ups are piloting microbial biosynthesis models aimed at replacing petroleum-based thiamine pathways. The European Commission has committed over €6 million in funding under the Horizon 2025 initiative for vitamin innovation.

Private-label supplement brands are investing heavily in marketing and product development around Vitamin B1. Over 250 start-ups globally launched thiamine-inclusive supplements in 2023, with over 40% based in North America. Custom formulation and subscription-based supplement models offer new commercial opportunities.

New Product Development

Product development around Vitamin B1 in 2023 focused on bioavailability, combination therapies, and eco-friendly manufacturing. DSM introduced a new line of thiamine mononitrate microencapsulated beads for controlled release in nutraceutical applications. This product improved bioavailability by 35% in clinical trials conducted across Europe.

BASF developed a dual-layer thiamine-vitamin C tablet that maintains structural integrity under high humidity, reducing degradation by 19%. Tianxin Pharmaceutical introduced injectable thiamine with prolonged half-life, now adopted in 23 clinical programs across Asia.

The functional food space saw new fortified snacks and beverages. In Japan, over 60 new drinks launched with added Vitamin B1, with consumer acceptance scores above 85% in taste trials. Brother Enterprises released a plant-based sports drink containing 1.5 mg of thiamine per serving in Q3 2023.

In animal nutrition, Huazhong launched a slow-release thiamine premix for poultry feed. Trials showed a 7.4% increase in feed efficiency and a 15% reduction in vitamin wastage over a 40-day broiler cycle. Innovations like these are supporting higher adoption across the feed industry.

Five Recent Developments

In February 2024, DSM expanded thiamine production in Switzerland by 1,200 metric tons with a focus on pharmaceutical purity.
In July 2023, Huazhong Pharmaceutical launched a new feed-grade Vitamin B1 premix for aquaculture in Southeast Asia.
In November 2023, BASF began pilot trials of bio-synthesized thiamine using genetically modified yeast.
In April 2024, Brother Enterprises introduced a powdered Vitamin B1 product for beverage mixes, gaining shelf space in over 1,800 Asian supermarkets.
In January 2024, Tianjin Golden World Group received EU-GMP certification for its new pharmaceutical-grade thiamine plant.

Report Coverage of Vitamin B1 (Thiamine) Market

This report comprehensively examines the global Vitamin B1 (Thiamine) Market, focusing on product types, applications, regional performance, and manufacturer competitiveness. It provides quantitative analysis of thiamine consumption by food grade, feed grade, and pharmaceutical grade, highlighting usage in food fortification, dietary supplements, and clinical nutrition.

The study outlines market dynamics such as pharmaceutical demand, raw material pricing volatility, and regulatory variations. It highlights region-specific trends, with Asia-Pacific leading in production, North America dominating supplement usage, and Europe focusing on sustainable sourcing.

Company profiles include top producers like DSM and Huazhong Pharmaceutical, assessing their production volumes, expansion initiatives, and global distribution networks. The report also captures investment trends, innovations in bioavailability, and key product launches across major consumer sectors.

It concludes with a timeline of five significant developments from 2023–2024, offering a complete view of the current and future state of the Vitamin B1 (Thiamine) Market.