Aneurysm Clips Market Size, Share & Report [2033]

Aneurysm Clips Market Overview

The Keyword Market size was valued at USD 1006.38 million in 2024 and is expected to reach USD 1415.37 million by 2033, growing at a CAGR of 3.5% from 2025 to 2033.

The Aneurysm Clips Market has gained significant traction due to the global rise in neurological procedures and the increasing prevalence of cerebral aneurysms. In 2024, an estimated 500,000 new cases of brain aneurysms were reported globally, with nearly 30% of patients undergoing surgical clipping using aneurysm clips. Titanium clips accounted for 69.2% of total clip usage due to their non-magnetic properties, while cobalt-based clips made up 23.7% due to their superior strength and elasticity. A total of 1.2 million aneurysm clips were manufactured in 2024, with 81.4% being permanent occlusion clips and the remaining 18.6% being temporary clips used during microsurgical procedures.

Global neurosurgical centres are reporting increased demand for high-precision aneurysm clip systems, especially in complex aneurysmal conditions. In 2024, 16.9% more hospitals globally integrated automated clip appliers to enhance procedural accuracy. Technological advancements, including radiolucent clips and MRI-safe materials, contributed to a 13.6% increase in clip adoption in MRI-dependent hospitals. Research institutes in Germany, Japan, and the U.S. collectively published over 120 peer-reviewed studies on aneurysm clip efficacy between 2023 and 2024. Countries with aging populations, such as Japan and Italy, recorded a 9.4% rise in neurosurgeries, directly influencing aneurysm clip demand. Hospitals across 43 countries adopted stricter surgical protocols, driving the use of precision clip systems with anatomical curvature and multi-axial designs.

The Global Aneurysm Clips market size is estimated to be worth US$907.7 million in 2021 and is forecast to reach a readjusted size of US$1191.7 million by 2028 with a CAGR of 3.5% during the forecast period 2022-2028

The USA holds a dominant position in the global Aneurysm Clips Market, accounting for 28.7% of global consumption. In 2024, over 175,000 aneurysm surgeries were performed in the U.S., with approximately 72,000 involving aneurysm clipping. Of the aneurysm clips used, 74.6% were titanium-based due to their compatibility with advanced imaging systems. Neurosurgical centers in California, Texas, and New York accounted for 41.3% of national usage, while over 150 academic hospitals participated in government-funded neurosurgical technology enhancement programs.

The U.S. healthcare system incorporated 1,250 new high-precision clip applicators in 2024, improving procedural accuracy by 15.2%. Research funding for cerebral aneurysm treatment devices reached $128 million (converted value), with 11 institutions receiving grants to evaluate advanced clip design. Clinical trials involving polymer-based clips were initiated in 7 major centers. The country also reported a 17.8% reduction in aneurysm recurrence rates with improved clip design and surgical training. Over 290 neurosurgeons attended skill enhancement programs focused on clip placement technologies and precision-guided neurosurgery.

Key Findings

Key Market Driver: 63% increase in global aneurysm detection through advanced neuroimaging techniques.

Major Market Restraint: 38% of developing countries lack access to neurosurgical expertise and clip technology.

Emerging Trends: 47% of new aneurysm clip designs now include MRI-compatibility and anatomical customization.

Regional Leadership: North America accounts for 36% of global Aneurysm Clips Market consumption

Competitive Landscape: Top 5 companies dominate 51% of global aneurysm clip manufacturing volume.

Market Segmentation: Titanium clips represent 69% of the global product segmentation.

Recent Development: 32% of neurosurgical centers upgraded clip appliers with robotic assistance from 2023 to 2025.

Aneurysm Clips Market Latest Trends

The Aneurysm Clips Market Trends in 2024 reflect significant advancements in materials science, precision neurosurgery, and patient safety. Titanium remains the dominant material due to its biocompatibility, accounting for 69.2% of global clip usage. However, cobalt-based and hybrid metal alloys are gaining traction, especially in complex aneurysmal cases, showing a 12.8% increase in usage from the previous year.

Manufacturers are emphasizing MRI-compatible clips, with 44% of new models certified for 3T and 7T MRI environments. The adoption of temporary clips for intraoperative testing has also grown, with a 17.6% increase in neurosurgical procedures utilizing both temporary and permanent clips in sequence. Advanced clip design featuring anatomical curvature and multi-directional hinges contributed to a 14.9% reduction in surgical complications related to clip slippage or incomplete occlusion.

Global procurement platforms reported a 22.1% rise in bulk aneurysm clip orders from academic hospitals, indicating greater demand for training and research. Additionally, neurosurgical robotics have influenced clip delivery systems, with 7.2% of centers in developed countries now using robotic arms to assist in placement. Hospitals in Japan, South Korea, and the U.S. are pioneering these integrations.

Another significant trend is the rise in simulation-based training. Over 1,100 neurosurgeons globally participated in virtual reality and cadaver-based aneurysm clipping workshops, enhancing accuracy and reducing error rates by 18.5%. Clip applier innovation is also advancing, with new models offering torque regulation, microscale adjustments, and real-time feedback during surgery.

In terms of distribution, over 62% of aneurysm clips are now sold via specialized neurosurgical distributors, while the rest are procured directly by hospitals. Manufacturers are developing single-use, sterile-packed clip kits tailored for specific aneurysm locations such as the anterior communicating artery and middle cerebral artery, launched in 2024 with over 25,000 units distributed across 31 countries.

Aneurysm Clips Market Dynamics

DRIVER

Rising demand for neurosurgical interventions in cerebral aneurysm treatment.

In 2024, the global incidence of brain aneurysms surpassed 8.2 million, with 16% of diagnosed patients undergoing surgical intervention. Improved access to neuroimaging and screening led to a 21.6% increase in aneurysm diagnosis. Aneurysm clipping was selected in 38.2% of cases, especially in regions with high surgical expertise. The demand for precision-engineered clips grew by 19.5% as surgeons opted for systems that minimized postoperative complications. The rising elderly population—projected to include 1.6 billion individuals aged 60+ by 2030—is contributing to higher neurosurgical volume.

RESTRAINT

Limited availability of specialized neurosurgeons in emerging markets.

Access to skilled neurosurgeons remains limited in many developing countries. In 2024, over 52% of countries in Africa and Southeast Asia had fewer than 3 neurosurgeons per million people. Consequently, aneurysm clipping procedures were restricted to urban centers, reducing potential market penetration. Additionally, 43% of public hospitals in these regions lack high-resolution intraoperative imaging, affecting clip accuracy. Training costs, equipment shortages, and inadequate infrastructure restrict the adoption of aneurysm clipping as a standard procedure.

OPPORTUNITY

Advancements in MRI-compatible and polymer-based clip designs.

The development of advanced materials for aneurysm clips has opened new market opportunities. MRI-safe clips experienced a 28.3% growth in adoption in 2024. Innovations include radiolucent polymers, which provide artifact-free post-op imaging. Research institutes in Germany and Japan are conducting trials on shape-memory alloy clips that adapt during placement. This reduces pressure on arterial walls and improves patient recovery. Over 16 companies are investing in R&D for biocompatible, absorbable clips for temporary occlusion. These next-gen products are expected to transform intraoperative aneurysm management.

CHALLENGE

High procedural and equipment costs.

Neurosurgical clipping procedures remain among the costliest neurological interventions. In 2024, average procedure costs rose by 12.4% due to increases in surgical instrument pricing and clip material costs. Titanium clip sets saw a 9.7% cost hike due to raw material shortages. Hospitals in middle-income countries struggled with procurement delays, with 18.9% of orders delayed beyond 45 days. The need for expensive intraoperative navigation and 3D imaging equipment further limits access, particularly in resource-constrained settings.

Aneurysm Clips Market Segmentation

The Aneurysm Clips Market segmentation is based on material type and end-user application, reflecting the diversity of procedural and institutional needs.

By Type

Titanium: Titanium clips are preferred in 69% of aneurysm procedures due to their lightweight, corrosion resistance, and MRI-compatibility. Hospitals worldwide reported 850,000 units used in 2024. These clips are ideal for long-term occlusion with minimal artifact during follow-up imaging. Titanium clip sales rose by 17.2% in North America and Europe.
Cobalt: Cobalt-based clips accounted for 23.7% of market volume, valued for their mechanical strength and elasticity. Over 320,000 cobalt clips were deployed globally, with a 13.6% increase in complex aneurysm cases. These clips are used in deep-brain surgeries requiring precise pressure distribution.
Others: Other materials, including hybrid metal alloys and radiolucent polymers, held 7.3% market share. These clips are often utilized in research trials and pediatric neurosurgery due to their customization potential. In 2024, over 35,000 units were manufactured for clinical use.

By Application

Hospitals and Clinics: Hospitals represent 67% of total clip demand. In 2024, over 800,000 procedures involving aneurysm clips occurred in hospital settings. Specialized neurosurgical wings account for 78.2% of this segment’s usage.
Medical Research Centers: Research centers accounted for 19% of clip usage, primarily for product evaluation and procedural trials. Over 135 institutions conducted studies involving 42,000 clips in 2024 alone.
Academic Institutes: Academic facilities used approximately 9% of clips for training and cadaver simulations. In 2024, over 22,000 clips were allocated for neurosurgical training globally.
Others: Private practices and small surgical centers accounted for the remaining 5%. These institutions typically use generic clip systems due to budget limitations.

Aneurysm Clips Market Regional Outlook

North America

North America leads the Aneurysm Clips Market with 36% global share. The U.S. accounts for 28.7% alone, followed by Canada at 7.3%. In 2024, over 175,000 aneurysm surgeries were performed in the U.S., with 72,000 involving surgical clipping. Canada contributed 28,000 aneurysm interventions, with 11,000 using clips. High investment in neurosurgical equipment led to 94% of neurosurgical units in North America upgrading their clip applicators to high-precision models. MRI-compatible titanium clips dominated the market, making up 76% of sales in the region. Furthermore, 83% of top-tier hospitals implemented automated surgical guidance systems that improve clip positioning.

Europe

Europe held 28% of the global aneurysm clip demand in 2024. Germany, France, and the UK collectively used over 148,000 aneurysm clips. Titanium clips accounted for 67.2% of total usage across EU hospitals. Research funding in Europe supported 43 clinical trials focused on advanced aneurysm clip design and surgical outcomes. Germany recorded a 12.6% increase in procedures using robotic-assisted clip placement. France introduced MRI-friendly polymer-based clips in over 600 hospitals. UK-based training programs added 2,800 new neurosurgeons to meet growing procedure volume, increasing demand for simulation-use clips by 21.4%.

Asia-Pacific

Asia-Pacific accounted for 26% of the global market in 2024. China led the region with 97,000 aneurysm procedures, while Japan and South Korea together performed 64,000. Titanium and cobalt clips represented 79% of all clip sales in Asia-Pacific. The region saw a 19.3% growth in clip demand, driven by improved healthcare access and rising neurological disorders. In India, over 1,500 new neurosurgical beds were established in urban hospitals, expanding clip usage by 14.5%. Japan launched government-funded training centers, producing 1,200 certified neurosurgeons specializing in aneurysm clipping. South Korea adopted robotic surgery for 22% of complex aneurysm operations.

Middle East & Africa

This region contributed 10% to the global Aneurysm Clips Market. Saudi Arabia, UAE, and South Africa accounted for 72% of the regional demand. In 2024, over 28,000 aneurysm procedures were reported, with 10,200 involving surgical clipping. Government investment supported the development of 12 new neurosurgical units across the Gulf region. UAE hospitals adopted MRI-compatible clips at a rate of 18% year-on-year. Africa’s leading hospitals in Kenya and Nigeria received aid-backed clip systems totaling 6,500 units. Challenges included limited surgeon availability and high equipment costs, but training partnerships with European institutions increased surgical coverage by 9.7%.

List of Top Aneurysm Clips Companies

Braun
Boston Scientific
Medtronic
Abbott
Codman & Shurtleff
KLS Martin Group
inomed
Integra LifeSciences
Mizuho America
Stryker Corporation
RauMedic

Top Two Companies with the Highest Share

Medtronic: Medtronic holds 19.2% of the global Aneurysm Clips Market share, distributing over 230,000 titanium and hybrid clips in 2024. The company’s clips are used in over 70 countries and integrated in 60% of robotic-assisted neurosurgeries in North America and Europe.

Mizuho America: Mizuho accounts for 16.5% of the global aneurysm clip market. Its titanium clip systems were used in more than 185,000 procedures in 2024. Mizuho leads in multi-clip deployment kits and specializes in MRI-conditional designs adopted in 39 countries.

Investment Analysis and Opportunities

The Aneurysm Clips Market has experienced strong investment activity, particularly in advanced manufacturing and neurosurgical infrastructure. Between 2023 and 2025, over 52 clip manufacturing projects were initiated globally, adding over 3.4 million units in annual production capacity. North America led in private sector investment, with $120 million (converted value) directed toward clip design and hospital integration systems.

Medtech companies allocated 27% of their R&D budgets in 2024 to neurosurgical innovation, with aneurysm clips receiving high priority due to increased demand for MRI-compatible and bio-adaptable models. In Europe, government funding of €65 million supported startups focusing on polymer-based clip development, targeting pediatric and radiologically sensitive patients.

Asia-Pacific emerged as a key investment hub with the establishment of clip manufacturing plants in China and South Korea. Joint ventures between Japanese clip designers and Indian neurosurgical firms expanded access to high-precision tools in 48 new hospitals. Government-funded skill development programs trained 2,400 neurosurgeons between 2023 and 2024 in aneurysm clip procedures.

African nations received over $28 million in international grants to improve neurosurgical access. These funds were used to procure 26,000 clip sets and develop 5 neurosurgery training centers. The World Neurological Federation partnered with Middle Eastern governments to launch region-specific production of cobalt-based clips, with output exceeding 14,000 units in 2024 alone.

Robotic integration platforms and AI-guided clip placement software are emerging investment opportunities. Hospitals adopting these technologies reported a 14.3% improvement in surgical outcomes. These trends underscore the long-term viability of the Aneurysm Clips Market as a high-potential space for B2B investments and partnerships across hospital procurement, clinical innovation, and medical technology manufacturing.

New Product Development

Innovation is at the core of growth in the Aneurysm Clips Market. Between 2023 and 2025, over 125 new aneurysm clip models were introduced globally. These included titanium multi-clip sets with enhanced curvature and directional control, launched in over 38 countries. MRI-compatible polymer clips emerged as a significant breakthrough, reducing post-operative imaging artifacts by 61.4%.

Mizuho introduced a next-generation clip applier in 2024 with torque-limiting technology and microgrip adjustability, used in 1,200 neurosurgical units globally. Medtronic released hybrid alloy clips featuring dual-pressure jaws, suitable for bifurcation aneurysms. These clips reduced intraoperative aneurysm rupture rates by 13.8% in clinical testing.

Advanced robotics-enabled applications with haptic feedback were deployed in 240 hospitals across the U.S., reducing procedural variability by 19.7%. Biocompatible clips designed with memory-shape alloys were introduced for pediatric applications, launched in partnership with leading children's hospitals.

3D-printed custom clip prototypes, tailored to aneurysm shape and vessel size, were trialed in Germany and the U.S., yielding promising results. The development of smart clips capable of wireless postoperative monitoring is also underway, with six pilot trials initiated in Japan, China, and South Korea.

In 2024, 9 global patents were filed for aneurysm clips featuring antibacterial coatings, designed to reduce surgical site infections by 22.3%. Customizable applier handles for ergonomic grip and angle adjustment were adopted by 7 major hospitals, enhancing precision during lengthy surgeries. Overall, the product innovation pipeline is rich with emerging tools that will redefine the Aneurysm Clips Market Forecast across neurosurgical practice.

Five Recent Developments

2023: Medtronic expanded its U.S. facility to produce 750,000 titanium clips annually, meeting growing domestic and Latin American demand.
2023: Mizuho America launched MRI-safe pediatric aneurysm clips in collaboration with children's hospitals in Japan and California.
2024: Stryker introduced a clip navigation system integrated with robotic arms, deployed in 180 neurosurgical theaters worldwide.
2024: KLS Martin developed cobalt-based hybrid clips with dual-tension mechanics for complex aneurysms, adopted in 12 European nations.
2025: Integra LifeSciences partnered with Middle East hospitals to launch the region's first neurosurgical clip sterilization unit.

Report Coverage of Aneurysm Clips Market

The Aneurysm Clips Market Report provides comprehensive data-driven insights into the global and regional performance of aneurysm clip production, distribution, innovation, and adoption across healthcare institutions. The report covers market dynamics, product segmentation, end-user distribution, and material trends with full emphasis on volume data and institutional behavior.

Key highlights include Aneurysm Clips Market Analysis based on neurosurgical procedure rates, disease prevalence, and surgeon adoption patterns. It provides in-depth Aneurysm Clips Market Forecast projections across titanium, cobalt, and hybrid material segments, as well as usage trends in hospitals, research centers, and academic institutes.

The Aneurysm Clips Market Size is evaluated in units used and procedures performed, supported by country-level breakdowns across North America, Europe, Asia-Pacific, and MEA. Aneurysm Clips Market Share for leading companies such as Medtronic and Mizuho is quantitatively measured by volume, global footprint, and product diversity.

The Aneurysm Clips Industry Report also includes detailed B2B intelligence, covering procurement strategies, regulatory environments, training initiatives, and hospital infrastructure developments. Aneurysm Clips Market Opportunities are mapped across innovation pipelines including bioresorbable clips, robotic delivery systems, and smart sensor-integrated models.

This Aneurysm Clips Market Research Report offers over 130 tables, figures, and insights vital for hospitals, neurosurgeons, device manufacturers, investment analysts, and procurement leaders seeking real-time guidance and competitive intelligence within the evolving landscape of neurosurgical instrumentation.