Global Organ-on-a-Chip Market Size, Status and Forecast 2021-2027

An organ-on-a-chip (OOC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems, a type of artificial organ. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing. Organ-on-a-chip technology not only incorporates multiple cell types but also involves engineering aspects, such as the guided spatial confinement of cells or the incorporation of sensors and microfluidic channels.
The primary focus of organ-on-a-chip technology is the re-creation of three key aspects of human physiology: the multicellular vascular or epithelial interfaces of organs (for example, blood vessel networks, lung and gut), which function as barriers in tissues; the tissue-level organization of parenchymal cells (for example, liver, heart, skeletal muscle and tumours), which are responsible for the key functional properties of an organ; and the systematic interaction of multiple organs (for example, drug absorption, distribution, metabolism and elimination involving the gut, circulation, liver and kidney).
In addition, the Blood-Brain Barrier is definitely more complex than a simple wall, controlling the passage of most solute that enters or leaves the brain. To address how this molecular sieve affects neural activity, some researchers have simulated the interaction between blood vessels and brain tissue on a series of interconnected "organ chips" when connected through this Blood-Brain Barrier (BBB) model. Endothelial cells, pericytes, astrocytes and neurons alter their gene expression. These technologies will achieve even more rapid development and application.
Major producers in the industry include Emulate, TissUse and Hesperos, which accounted for 12.71%, 10.05% and 8.11% of revenue, respectively.

Market Analysis and Insights: Global Organ-on-a-Chip Market
The global Organ-on-a-Chip market size is projected to reach US$ 424.7 million by 2027, from US$ 41 million in 2020, at a CAGR of 39.9% during 2021-2027.
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Global Organ-on-a-Chip Scope and Market Size
Organ-on-a-Chip market is segmented by company, region (country), by Type, and by Application. Players, stakeholders, and other participants in the global Organ-on-a-Chip market will be able to gain the upper hand as they use the report as a powerful resource. The segmental analysis focuses on revenue and forecast by Type and by Application in terms of revenue and forecast for the period 2016-2027.

Segment by Type
Liver-on-a-chip
Kidney-on-a-chip
Lung-on-a-chip
Heart-on-a-chip
Intestine-on-a-chip
Brain-on-a-chip
Other Organs

Segment by Application
Pharmaceutical and Biotechnology Companies
Academic and Research Institutes
Cosmetics Industry
Other End Users

By Region
North America
U.S.
Canada
Europe
Germany
France
U.K.
Italy
Russia
Nordic
Rest of Europe
Asia-Pacific
China
Japan
South Korea
Southeast Asia
India
Australia
Rest of Asia
Latin America
Mexico
Brazil
Rest of Latin America
Middle East & Africa
Turkey
Saudi Arabia
UAE
Rest of MEA

By Company
Emulate
TissUse
Hesperos
CN Bio Innovations
Tara Biosystems
Draper Laboratory
Mimetas
Nortis
Micronit Microtechnologies B.V.
Kirkstall
Cherry Biotech SAS
Else Kooi Laboratory

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