Pre-order Enquiry
Download Free Sample
Healthcare
Aerospace & Defence
Agriculture
Automations
Chemicals & Advanced Materials
Food & Beverages
Information & Communication Technology
Oil & Gas
Power & Energy
Market Analysis and Insights: Global Bio Pharma Buffer Market
A buffer solution is comprised of a weak conjugate acid-base pair, for example, a weak acid and its conjugate base, or a weak base and its conjugate acid. Small quantities of other acids or bases are neutralized when added to the solution, and as a result, the solution resists changes in pH. Solutions with stable pH are required for the processing of protein-based biologic APIs because of their sensitivity to changes in pH. The stable pH range and capacity (the amount of acid/base that can be added without a change in pH) of a buffer are determined by the conjugate acid-base pair.
Most purification steps for downstream processing of biologics require buffers to equilibrate, condition, wash, elute, or concentrate the product. They are used in product isolation and purification steps to facilitate protein capture and polishing and also in the filtration process for the removal of viruses or depyrogenation. Aqueous solutions are also required for cleaning and disinfecting downstream processing equipment, such as chromatography matrices and membrane filtration systems. The main equipment involved in downstream processing with buffers includes mixers for buffer preparation, as well as equipment for purification, including packed-bed chromatography systems, fluidized beds, ultrafiltration and diafiltration membranes, microfiltration membranes, depth filtration cartridges, and virus-removal systems.
Due to the COVID-19 pandemic, the global Bio Pharma Buffer market size is estimated to be worth US$ 841.4 million in 2022 and is forecast to a readjusted size of US$ 1376.7 million by 2029 with a CAGR of 7.2% during the forecast period 2023-2029. Fully considering the economic change by this health crisis, Phosphates Type accounting for % of the Bio Pharma Buffer global market in 2022, is projected to value US$ million by 2029, growing at a revised % CAGR from 2023 to 2029. While Research Institution segment is altered to an % CAGR throughout this forecast period.
The key players are Avantor, Alfa Aesar (Thermo Fisher), Merck, Lonza, Bio-Rad, BD, GE, Healthcare, Promega Corporation, Hamilton Company, XZL BIO-TECHNOLOGY, SRL and so on. According to the revenue of these companies, we can know that the Bio Pharma Buffer industry is relative concentrated. Because the top 6 companies have more than 70% market share.
Global Bio Pharma Buffer Scope and Market Size
The global Bio Pharma Buffer market is segmented by company, region (country), type and application. Players, stakeholders, and other participants in the global Bio Pharma Buffer market will be able to gain the upper hand as they use the report as a powerful resource. The segmental analysis focuses on sales, revenue and forecast by region (country), type and application for the period 2018-2029.
Segment by Type
Phosphates Type
Acetates Type
TRIS Type
Others
Segment by Application
Research Institution
Pharmaceutical Industry
Others
By Region
United States
Europe
China
Japan
Southeast Asia
India
Other Regions
By Company
Avantor
Alfa Aesar (Thermo Fisher)
Merck
Lonza
Bio-Rad
BD
GE Healthcare
Promega Corporation
Hamilton Company
XZL BIO-TECHNOLOGY
SRL
A buffer solution is comprised of a weak conjugate acid-base pair, for example, a weak acid and its conjugate base, or a weak base and its conjugate acid. Small quantities of other acids or bases are neutralized when added to the solution, and as a result, the solution resists changes in pH. Solutions with stable pH are required for the processing of protein-based biologic APIs because of their sensitivity to changes in pH. The stable pH range and capacity (the amount of acid/base that can be added without a change in pH) of a buffer are determined by the conjugate acid-base pair.
Most purification steps for downstream processing of biologics require buffers to equilibrate, condition, wash, elute, or concentrate the product. They are used in product isolation and purification steps to facilitate protein capture and polishing and also in the filtration process for the removal of viruses or depyrogenation. Aqueous solutions are also required for cleaning and disinfecting downstream processing equipment, such as chromatography matrices and membrane filtration systems. The main equipment involved in downstream processing with buffers includes mixers for buffer preparation, as well as equipment for purification, including packed-bed chromatography systems, fluidized beds, ultrafiltration and diafiltration membranes, microfiltration membranes, depth filtration cartridges, and virus-removal systems.
Due to the COVID-19 pandemic, the global Bio Pharma Buffer market size is estimated to be worth US$ 841.4 million in 2022 and is forecast to a readjusted size of US$ 1376.7 million by 2029 with a CAGR of 7.2% during the forecast period 2023-2029. Fully considering the economic change by this health crisis, Phosphates Type accounting for % of the Bio Pharma Buffer global market in 2022, is projected to value US$ million by 2029, growing at a revised % CAGR from 2023 to 2029. While Research Institution segment is altered to an % CAGR throughout this forecast period.
The key players are Avantor, Alfa Aesar (Thermo Fisher), Merck, Lonza, Bio-Rad, BD, GE, Healthcare, Promega Corporation, Hamilton Company, XZL BIO-TECHNOLOGY, SRL and so on. According to the revenue of these companies, we can know that the Bio Pharma Buffer industry is relative concentrated. Because the top 6 companies have more than 70% market share.
Global Bio Pharma Buffer Scope and Market Size
The global Bio Pharma Buffer market is segmented by company, region (country), type and application. Players, stakeholders, and other participants in the global Bio Pharma Buffer market will be able to gain the upper hand as they use the report as a powerful resource. The segmental analysis focuses on sales, revenue and forecast by region (country), type and application for the period 2018-2029.
Segment by Type
Phosphates Type
Acetates Type
TRIS Type
Others
Segment by Application
Research Institution
Pharmaceutical Industry
Others
By Region
United States
Europe
China
Japan
Southeast Asia
India
Other Regions
By Company
Avantor
Alfa Aesar (Thermo Fisher)
Merck
Lonza
Bio-Rad
BD
GE Healthcare
Promega Corporation
Hamilton Company
XZL BIO-TECHNOLOGY
SRL
Frequently Asked Questions
This market study covers the global and regional market with an
in-depth analysis of the
overall growth prospects...
- By product type
- By End User/Applications
- By Technology
- By Region
The report provides a detailed evaluation of the market by
highlighting information on
different aspects including drivers, restraints...
