Demineralized bone matrix (DBM) is allograft bone that has had the inorganic mineral removed, leaving behind the organic "collagen" matrix. It was first discovered by Marshall Urist in 1965 that the removal of the bone mineral exposes more biologically active bone morphogenetic proteins. These growth factors modulate the differentiation of progenitor cells into osteoprogenitor cells, which are responsible for bone and cartilage formation. As a result of the demineralization process, DBM is more biologically active than undemineralized bone grafts; conversely the mechanical properties are significantly diminished.
The classification of demineralized bone matrix (DBM) includes gel, putty, putty with chips, and the proportion of Putty in 2017 is about 46%, and the proportion is in decreasing trend from 2013 to 2017.
Demineralized bone matrix (DBM) is widely used in dental surgery, spine surgery, trauma surgery. The most proportion of demineralized bone matrix (DBM) is for spine surgery, and the proportion in 2017 is about 78%.
North America is the largest consumption place, with a consumption market share nearly 56% in 2017. Following North America, Europe is the second largest consumption place with the consumption market share of 30%.
In 2019, the market size of Demineralized Bone Matrix is 620 million US$ and it will reach 940 million US$ in 2025, growing at a CAGR of 5.4% from 2019; while in China, the market size is valued at xx million US$ and will increase to xx million US$ in 2025, with a CAGR of xx% during forecast period.
In this report, 2018 has been considered as the base year and 2019 to 2025 as the forecast period to estimate the market size for Demineralized Bone Matrix.

This report studies the global market size of Demineralized Bone Matrix, especially focuses on the key regions like United States, European Union, China, and other regions (Japan, Korea, India and Southeast Asia).
This study presents the Demineralized Bone Matrix production, revenue, market share and growth rate for each key company, and also covers the breakdown data (production, consumption, revenue and market share) by regions, type and applications. history breakdown data from 2014 to 2019, and forecast to 2025.
For top companies in United States, European Union and China, this report investigates and analyzes the production, value, price, market share and growth rate for the top manufacturers, key data from 2014 to 2019.

In global market, the following companies are covered:
J &J (DePuy Synthes)
Zimmer Biomet
Stryker
SeaSpine
Straumann
Xtant Medical
Wright Medical Group
RTI Surgical
Hans Biomed
Arthrex

Market Segment by Product Type
Gel
Putty
Putty with Chips
Others

Market Segment by Application
Dental
Spine Surgery
Trauma Surgery

Key Regions split in this report: breakdown data for each region.
United States
China
European Union
Rest of World (Japan, Korea, India and Southeast Asia)

The study objectives are:
To analyze and research the Demineralized Bone Matrix status and future forecast in United States, European Union and China, involving sales, value (revenue), growth rate (CAGR), market share, historical and forecast.
To present the key Demineralized Bone Matrix manufacturers, presenting the sales, revenue, market share, and recent development for key players.
To split the breakdown data by regions, type, companies and applications
To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
To identify significant trends, drivers, influence factors in global and regions
To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market

In this study, the years considered to estimate the market size of Demineralized Bone Matrix are as follows:
History Year: 2014-2018
Base Year: 2018
Estimated Year: 2019
Forecast Year 2019 to 2025