Table of Contents Introduction Traumatic Brain Injury - Overview Traumatic Brain Injury - Therapeutics Development Traumatic Brain Injury - Therapeutics Assessment Traumatic Brain Injury - Companies Involved in Therapeutics Development Traumatic Brain Injury - Drug Profiles Traumatic Brain Injury - Dormant Projects Traumatic Brain Injury - Discontinued Products Traumatic Brain Injury - Product Development Milestones Appendix

List of Tables Number of Products under Development for Traumatic Brain Injury, H1 2019 Number of Products under Development by Companies, H1 2019 Number of Products under Development by Companies, H1 2019 (Contd..1), H1 2019 Number of Products under Development by Companies, H1 2019 (Contd..2), H1 2019 Number of Products under Development by Companies, H1 2019 (Contd..3), H1 2019 Number of Products under Development by Universities/Institutes, H1 2019 Products under Development by Companies, H1 2019 Products under Development by Companies, H1 2019 (Contd..1), H1 2019 Products under Development by Companies, H1 2019 (Contd..2), H1 2019 Products under Development by Companies, H1 2019 (Contd..3), H1 2019 Products under Development by Companies, H1 2019 (Contd..4), H1 2019 Products under Development by Universities/Institutes, H1 2019 Number of Products by Stage and Target, H1 2019 Number of Products by Stage and Target, H1 2019 (Contd..1), H1 2019 Number of Products by Stage and Target, H1 2019 (Contd..2), H1 2019 Number of Products by Stage and Mechanism of Action, H1 2019 Number of Products by Stage and Mechanism of Action, H1 2019 (Contd..1), H1 2019 Number of Products by Stage and Mechanism of Action, H1 2019 (Contd..2), H1 2019 Number of Products by Stage and Mechanism of Action, H1 2019 (Contd..3), H1 2019 Number of Products by Stage and Route of Administration, H1 2019 Number of Products by Stage and Molecule Type, H1 2019 Traumatic Brain Injury - Pipeline by Alexion Pharmaceuticals Inc, H1 2019 Traumatic Brain Injury - Pipeline by ALSP Inc, H1 2019 Traumatic Brain Injury - Pipeline by AlzeCure Pharma AB, H1 2019 Traumatic Brain Injury - Pipeline by AMAG Pharmaceuticals Inc, H1 2019 Traumatic Brain Injury - Pipeline by Amarantus Bioscience Holdings Inc, H1 2019 Traumatic Brain Injury - Pipeline by Anagin Inc, H1 2019 Traumatic Brain Injury - Pipeline by Aptinyx Inc, H1 2019 Traumatic Brain Injury - Pipeline by Athersys Inc, H1 2019 Traumatic Brain Injury - Pipeline by Avanir Pharmaceuticals Inc, H1 2019 Traumatic Brain Injury - Pipeline by Biogen Inc, H1 2019 Traumatic Brain Injury - Pipeline by CalciMedica Inc, H1 2019 Traumatic Brain Injury - Pipeline by Cantex Pharmaceuticals Inc, H1 2019 Traumatic Brain Injury - Pipeline by CereSpir Inc, H1 2019 Traumatic Brain Injury - Pipeline by Cognosci Inc, H1 2019 Traumatic Brain Injury - Pipeline by Complement Pharma BV, H1 2019 Traumatic Brain Injury - Pipeline by Eisai Co Ltd, H1 2019 Traumatic Brain Injury - Pipeline by Epigen Biosciences Inc, H1 2019 Traumatic Brain Injury - Pipeline by Hemarina SA, H1 2019 Traumatic Brain Injury - Pipeline by Hoverink Biotechnologies Inc, H1 2019 Traumatic Brain Injury - Pipeline by International Stem Cell Corp, H1 2019 Traumatic Brain Injury - Pipeline by Ischemix Inc, H1 2019 Traumatic Brain Injury - Pipeline by JT Pharmaceuticals Inc, H1 2019 Traumatic Brain Injury - Pipeline by Levolta Pharmaceuticals Inc, H1 2019 Traumatic Brain Injury - Pipeline by Mapreg SAS, H1 2019 Traumatic Brain Injury - Pipeline by Neuralstem Inc, H1 2019 Traumatic Brain Injury - Pipeline by Neuren Pharmaceuticals Ltd, H1 2019 Traumatic Brain Injury - Pipeline by NeuroNascent Inc, H1 2019 Traumatic Brain Injury - Pipeline by NeuroVive Pharmaceutical AB, H1 2019 Traumatic Brain Injury - Pipeline by New World Laboratories Inc, H1 2019 Traumatic Brain Injury - Pipeline by NoNO Inc, H1 2019 Traumatic Brain Injury - Pipeline by NuvOx Pharma LLC, H1 2019 Traumatic Brain Injury - Pipeline by Nyrada Inc, H1 2019 Traumatic Brain Injury - Pipeline by Oxeia Biopharmaceuticals Inc, H1 2019 Traumatic Brain Injury - Pipeline by Peptron Inc, H1 2019 Traumatic Brain Injury - Pipeline by Prevacus Inc, H1 2019 Traumatic Brain Injury - Pipeline by ProThera Biologics Inc, H1 2019 Traumatic Brain Injury - Pipeline by QR Pharma Inc, H1 2019 Traumatic Brain Injury - Pipeline by Qrons Inc, H1 2019 Traumatic Brain Injury - Pipeline by Radikal Therapeutics Inc, H1 2019 Traumatic Brain Injury - Pipeline by RegeneRx Biopharmaceuticals Inc, H1 2019 Traumatic Brain Injury - Pipeline by Resolys Bio Inc, H1 2019 Traumatic Brain Injury - Pipeline by Rubicon Biotechnology Inc, H1 2019 Traumatic Brain Injury - Pipeline by Sage Therapeutics Inc, H1 2019 Traumatic Brain Injury - Pipeline by Silver Creek Pharmaceuticals Inc, H1 2019 Traumatic Brain Injury - Pipeline by STATegics Inc, H1 2019 Traumatic Brain Injury - Pipeline by Stemedica Cell Technologies Inc, H1 2019 Traumatic Brain Injury - Pipeline by SynZyme Technologies LLC, H1 2019 Traumatic Brain Injury - Pipeline by Tetra Discovery Partners LLC, H1 2019 Traumatic Brain Injury - Pipeline by Therapeutic Solutions International Inc, H1 2019 Traumatic Brain Injury - Pipeline by Therapix Biosciences Ltd, H1 2019List of Figures Number of Products under Development for Traumatic Brain Injury, H1 2019 Number of Products under Development by Companies, H1 2019 Number of Products under Development by Universities/Institutes, H1 2019 Number of Products by Top 10 Targets, H1 2019 Number of Products by Stage and Top 10 Targets, H1 2019 Number of Products by Top 10 Mechanism of Actions, H1 2019 Number of Products by Stage and Top 10 Mechanism of Actions, H1 2019 Number of Products by Top 10 Routes of Administration, H1 2019 Number of Products by Stage and Top 10 Routes of Administration, H1 2019 Number of Products by Top 10 Molecule Types, H1 2019 Number of Products by Stage and Top 10 Molecule Types, H1 2019

Alexion Pharmaceuticals Inc ALSP Inc AlzeCure Pharma AB AMAG Pharmaceuticals Inc Amarantus Bioscience Holdings Inc Anagin Inc Aptinyx Inc Athersys Inc Avanir Pharmaceuticals Inc Biogen Inc CalciMedica Inc Cantex Pharmaceuticals Inc CereSpir Inc Cognosci Inc Complement Pharma BV Eisai Co Ltd Epigen Biosciences Inc Hemarina SA Hoverink Biotechnologies Inc International Stem Cell Corp Ischemix Inc JT Pharmaceuticals Inc Levolta Pharmaceuticals Inc Mapreg SAS Neuralstem Inc Neuren Pharmaceuticals Ltd NeuroNascent Inc NeuroVive Pharmaceutical AB New World Laboratories Inc NoNO Inc NuvOx Pharma LLC Nyrada Inc Oxeia Biopharmaceuticals Inc Peptron Inc Prevacus Inc ProThera Biologics Inc QR Pharma Inc Qrons Inc Radikal Therapeutics Inc RegeneRx Biopharmaceuticals Inc Resolys Bio Inc Rubicon Biotechnology Inc Sage Therapeutics Inc Silver Creek Pharmaceuticals Inc STATegics Inc Stemedica Cell Technologies Inc SynZyme Technologies LLC Tetra Discovery Partners LLC Therapeutic Solutions International Inc Therapix Biosciences Ltd TikoMed AB Tiziana Life Sciences Plc vasopharm GmbH VG Life Sciences Inc Virogenomics BioDevelopment Inc