Table of Contents 1. Research Methodology 2. Executive Summary 3. Strategic Recommendations 4. Proton Therapy Market Outlook 5. Global Proton Therapy Market: Growth and Forecast 5.1 By Value (2013-2017) 5.2 By Value (2018-2023) 6. Global Proton Therapy Market: Segment Analysis 6.1 Global Proton Therapy Market Size, By Product: Breakdown (%) 6.1.1 Global Proton Therapy Market Size, By Product, 2017 (%) 6.1.2 Global Proton Therapy Market Size, By Product, 2023 (%) 6.2 Global Proton Therapy Equipment Market, By Value (2013-2023) 6.3 Global Proton Therapy Services Market, By Value (2013-2023) 6.4 Global Proton Therapy Market Size, By Type: Breakdown (%) 6.4.1 Global Proton Therapy Market Size, By Type, 2017 (%) 6.4.2 Global Proton Therapy Market Size, By Type, 2023 (%) 6.5 Global Single Room Proton Therapy Market, By Value (2013-2023) 6.6 Global Multi-Room Proton Therapy Market, By Value (2013-2023) 7. Global Proton Therapy Market: Regional Analysis 7.1 Global Proton Therapy Market Size, By Region : Breakdown (%) 7.1.1 Global Proton Therapy Market Size, By Region, 2017 (%) 7.1.2 Global Proton Therapy Market Size, By Region, 2023 (%) 7.2 North America Proton Therapy Market: Growth and Forecast 7.2.1 By Value (2013-2017) 7.2.2 By Value (2018-2023) 7.2.3 By Product, By Value (2013-2017) 7.2.4 By Product, By Value (2018-2023) 7.2.5 By Type, By Value (2013-2017) 7.2.6 By Type, By Value (2018-2023) 7.3 North America Proton Therapy Market: Country Analysis (U.S) 7.3.1 U.S Proton Therapy Market, By Value (2013-2023) 7.3.2 U.S Proton Therapy Market, By Product, By Value (2013-2017) 7.3.3 U.S Proton Therapy Market, By Product, By Value (2018-2023) 7.4 Europe Proton Therapy Market: Growth and Forecast 7.4.1 By Value (2013-2017) 7.4.2 By Value (2018-2023) 7.4.3 By Product, By Value (2013-2017) 7.4.4 By Product, By Value (2018-2023) 7.4.5 By Type, By Value (2013-2017) 7.4.6 By Type, By Value (2018-2023) 7.5 Europe Proton Therapy Market: Country Analysis (Germany and France) 7.5.1 Germany Proton Therapy Market, By Value (2013-2023) 7.5.2 Germany Proton Therapy Market, By Product, By Value (2013-2017) 7.5.3 Germany Proton Therapy Market, By Product, By Value (2018-2023) 7.5.4 France Proton Therapy Market, By Value (2013-2023) 7.5.5 France Proton Therapy Market, By Product, By Value (2013-2017) 7.5.6 France Proton Therapy Market, By Product, By Value (2018-2023) 7.6 APAC Proton Therapy Market: Growth and Forecast 7.6.1 By Value (2013-2017) 7.6.2 By Value (2018-2023) 7.6.3 By Product, By Value (2013-2017) 7.6.4 By Product, By Value (2018-2023) 7.6.5 By Type, By Value (2013-2017) 7.6.6 By Type, By Value (2018-2023) 7.7 APAC Proton Therapy Market: Country Analysis (Japan and China) 7.7.1 Japan Proton Therapy Market, By Value (2013-2023) 7.7.2 Japan Proton Therapy Market, By Product, By Value (2013-2017) 7.7.3 Japan Proton Therapy Market, By Product, By Value (2018-2023) 7.7.4 China Proton Therapy Market, By Value (2013-2023) 7.7.5 China Proton Therapy Market, By Product, By Value (2013-2017) 7.7.6 China Proton Therapy Market, By Product, By Value (2018-2023) 7.8 ROW Proton Therapy Market: Growth and Forecast 7.8.1 By Value (2013-2017) 7.8.2 By Value (2018-2023) 7.8.3 By Product, By Value (2013-2017) 7.8.4 By Product, By Value (2018-2023) 7.8.5 By Type, By Value (2013-2017) 7.8.6 By Type, By Value (2018-2023) 8. Global Proton Therapy Market Dynamics 8.1 Global Proton Therapy Market Drivers 8.2 Global Proton Therapy Market Restraints 9. Global Proton Therapy Market Trends 10. Porter Five Force Analysis 11. SWOT Analysis 12. Competitive Landscape 12.1 Company Share Analysis of Key Industry Players 13. Policy and Regulatory Landscape 14. Company Profiles 14.1 IBA Proton Therapy Inc. 14.2 Varian Medical Systems 14.3 Advanced Oncotherapy plc 14.4 Mevion Medical Systems 14.5 Optivus Proton Therapy, Inc. 14.6 ProTom International 14.7 ProNova Solutions LLC 14.8 Sumitomo Heavy Industries, Inc. 14.9 Hitachi

List of Figures Figure 1: Standard Radiotherapy Versus Proton Therapy for the Treatment of Tumor Figure 2: Common Treatment Modalities for Cancer Figure 3: Cancer Treatment Flowchart Figure 4: Proton Therapy Market Segmentation Flowchart Figure 5: Global Proton Therapy Market Size, By Value, 2013-2017 (USD Million) Figure 6: Global Proton Therapy Market Size, By Value, Forecast, 2018-2023 (USD Million) Figure 7: Projected global population (In Billions) Figure 8: Population ages 65 and above, By Select Region, 2013-2017 (% of total) Figure 9: Projected global population aged 60 years & above (In Billions) Figure 10: Global Health Expenditure Per Capita, By Select Countries, 2016 (In USD) Figure 11: Global Health Expenditure Per Capita, (2012-2016, USD Trillion) Figure 12: Global Burden of Cancer Figure 13: Prevalence and Epidemiology of Cancer Worldwide Figure 14: 5 Year Survival Rate, Breast and Colorectal Cancer Figure 15: Types of cancer for which clinical trials using proton therapy treatment are being conducted Figure 16: Global Prevalence of Different Type of Cancer, 2017 (In Thousands) Figure 17: Global Prevalence of Prostate Cancer (2013-2017, Thousands) Figure 18: Global Proton Therapy Market Size, By Product, 2017 (%) Figure 19: Global Proton Therapy Market Size, By Type, 2023 (%) Figure 20: Global Proton Therapy Equipment Market, By Value, 2013-2017 (USD Million) Figure 21: Global Proton Therapy Equipment Market, By Value, Forecast, 2018-2023 (USD Million) Figure 22: Global Proton Therapy Services Market, By Value, 2013-2017 (USD Million) Figure 23: Global Proton Therapy Services Market, By Value, Forecast, 2018-2023 (USD Million) Figure 24: Global Proton Therapy Market Size, By Type, 2017 (%) Figure 25: Global Proton Therapy Market Size, By Type, 2023 (%) Figure 26: Global Single Room Proton Therapy Market, By Value, 2013-2017 (USD Million) Figure 27: Global Single Room Proton Therapy Market, By Value, Forecast, 2018-2023 (USD Million) Figure 28: Global Multi-Room Proton Therapy Market, By Value, 2013-2017 (USD Million) Figure 29: Global Multi-Room Proton Therapy Market, By Value, Forecast, 2018-2023 (USD Million) Figure 30: Single and Multi-Room Proton Therapy Characteristics Figure 31: Global Proton Therapy Market Size, By Region, 2017 (%) Figure 32: Global Proton Therapy Market Size, By Region, 2023 (%) Figure 33: North America Proton Therapy Market Size, By Value, 2013-2017 (USD Million) Figure 34: North America Proton Therapy Market Size, By Value, Forecast, 2018-2023 (USD Million) Figure 35: Prevalence of Different Type of Cancer in North America in year 2016 & 2017 ( In Hundreds) Figure 36: North America, Cancer Incidence (In Millions) Figure 37: North America, Cancer Incidence, By Type, 2019E (In %) Figure 38: North America Population above 65 year, 2015, 2030F, & 2050F (In Millions) Figure 39: North America Proton Therapy Market: By Product, By Value, 2013-2017 (USD Million) Figure 40: North America Proton Therapy Market: By Product, By Value, 2018E-2023F (USD Million) Figure 41: North America Proton Therapy Market: By Type, By Value, 2013-2017 (USD Million) Figure 42: North America Proton Therapy Market: By Type, By Value, 2018E-2023F (USD Million) Figure 43: U.S. Proton Therapy Market Size, By Value, 2013-2023 (USD Million) Figure 44: Estimated New Cases of Cancer in the United States, By Type 2018 (In %) Figure 45: Estimated New Cases of Cancer in the United States, 2014-2018 (In Thousands) Figure 46: United States, Proton Therapy, Reimbursement Price Per Treatment Case*, 2014-2017 (In USD Thousands) Figure 47: United States, Proton Therapy Market, Reimbursement Landscape Figure 48: United States, Proton Therapy Market, By Company Share, 2017 (%) Figure 49: U.S Proton Therapy Market: By Product, By Value, 2013-2017 (USD Million) Figure 50: U.S Proton Therapy Market: By Product, By Value, 2018E-2023F (USD Million) Figure 51: North America Proton Therapy Market, Country Share, 2013-2017 (% of Total) Figure 52: North America Proton Therapy Market, Country Share, 2018F-2023F (% of Total) Figure 53: Europe Proton Therapy Market Size, By Value, 2013-2017 (USD Million) Figure 54: Europe Proton Therapy Market Size, By Value, Forecast, 2018-2023 (USD Million) Figure 55: Europe, Cancer Incidence, 2019E-2035F (In Millions) Figure 56: Europe, Cancer Incidence, By Type, 2019E Figure 57: Prevalence of Different Type of Cancer in Western Europe in year 2016 & 2017 ( In Thousands) Figure 58: Europe Proton Therapy Market: By Product, By Value, 2013-2017 (USD Million) Figure 59: Europe Proton Therapy Market: By Product, By Value, 2018E-2023F (USD Million) Figure 60: Europe Proton Therapy Market: By Type, By Value, 2013-2017 (USD Million) Figure 61: Europe Proton Therapy Market: By Type, By Value, 2013-2017 (USD Million) Figure 62: Germany Proton Therapy Market Size, By Value, 2013-2023 (USD Million) Figure 63: Prevalence of Different Type of Cancer in Germany in year 2016 & 2017 ( In Hundreds) Figure 64: Germany Proton Therapy Market: By Product, By Value, 2013-2017 (USD Million) Figure 65: Germany Proton Therapy Market: By Product, By Value, 2018E-2023F (USD Million) Figure 66: France Proton Therapy Market Size, By Value, 2013-2023 (USD Million) Figure 67: Prevalence of Different Type of Cancer in France in year 2016 & 2017 ( In Hundreds) Figure 68: France Proton Therapy Market: By Product, By Value, 2013-2017 (USD Million) Figure 69: France Proton Therapy Market: By Product, By Value, 2018E-2023F (USD Million) Figure 70: Europe Proton Therapy Market, Country Share, Historic, 2013-2017(% of Total) Figure 71: Europe Proton Therapy Market, Country Share, Forecast, 2018-2023 (% of Total) Figure 72: APAC Proton Therapy Market Size, By Value, 2013-2017 (USD Million) Figure 73: APAC Proton Therapy Market Size, By Value, Forecast, 2018-2023 (USD Million) Figure 74: Estimated number of deaths from prostate cancer in 2012 and 2030 Figure 75: World health expenditure as % of GDP Figure 76: Population ages 65 and above, APAC Region, By Select Countries, 2017 (% of total) Figure 77: Population ages 65 and above, APAC Region, By Select Countries, 2050 (% of total) Figure 78: APAC Proton Therapy Market: By Product, By Value, 2013-2017 (USD Million) Figure 79: APAC Proton Therapy Market: By Product, By Value, 2018E-2023F (USD Million) Figure 80: APAC Proton Therapy Market: By Type, By Value, 2013-2017 (USD Million) Figure 81: APAC Proton Therapy Market: By Type, By Value, 2018E-2023F (USD Million) Figure 82: Japan Proton Therapy Market Size, By Value, 2013-2023 (USD Million) Figure 83: Japan Per Capita Health Expenditure (2012-2016,USD) Figure 84: Japan Population 65 Years & Above (% of Total), 2012-2016 Figure 85: Prevalence of Different Type of Cancer in Japan in year 2016 & 2017 ( In Hundreds) Figure 86: Japan Proton Therapy Market: By Product, By Value, 2013-2017 (USD Million) Figure 87: Japan Proton Therapy Market: By Product, By Value, 2018E-2023F (USD Million) Figure 88: China Proton Therapy Market Size, By Value, 2013-2023 (USD Million) Figure 89: China, GDP Growth Per Year, 2015-2019 (In %) Figure 90: China, Share of Urban Population, 2012-2017 (In %) Figure 91: China, Total Population, 2013-2021F (In Billion) Figure 92: Prevalence of Different Type of Cancer in China in year 2016 & 2017 ( In Hundreds) Figure 93: China Proton Therapy Market: By Product, By Value, 2013-2017 (USD Million) Figure 94: China Proton Therapy Market: By Product, By Value, 2018E-2023F (USD Million) Figure 95: Asia Pacific W/O Japan, Proton Therapy Market, By Company Share, 2017 (%) Figure 96: Japan, Proton Therapy Market, By Company Share, 2017 (%) Figure 97: APAC Proton Therapy Market, Country Share, Historic, 2013-2017 (% of Total) Figure 98: APAC Proton Therapy Market, Country Share, Forecast, 2018-2023 (% of Total) Figure 99: ROW Proton Therapy Market Size, By Value, 2013-2023 (USD Million) Figure 100: Middle East and North Africa, GDP, 2012-2017 (In USD Trillion) Figure 101: Latin America and Caribbean, Share of Urban Population in Total Population, 2012-2017 (In %) Figure 102: Prevalence of Different Type of Cancer in Middle East and North Africa in year 2016 & 2017 ( In Hundreds) Figure 103: Prevalence of Different Type of Cancer in Brazil in year 2016 & 2017 ( In Hundreds) Figure 104: ROW Proton Therapy Market: By Product, By Value, 2013-2017 (USD Million) Figure 105: ROW Proton Therapy Market: By Product, By Value, 2018E-2023F (USD Million) Figure 106: ROW Proton Therapy Market: By Type, By Value, 2013-2017 (USD Million) Figure 107: ROW Proton Therapy Market: By Type, By Value, 2018E-2023F (USD Million) Figure 108: Proton Machine Market, By Company Projection, By Orders Placed Figure 109: Share of Major Players in Europe and ROW Region, Proton Therapy Market, 2017 (%) Figure 110: Proton Therapy Systems, By Company Figure 111: Ion Beam Application, Revenue, 2013-2017 (In USD Million) Figure 112: Ion Beam Application, Revenue, By Business Segment, 2017 (In %) Figure 113: Ion Beam Application, Net Sales and Services, By Geographic Region, 2017 (In %) Figure 114: Varian Medical Systems, Revenue, 2014-2018 (In USD Billion) Figure 115: Varian Medical Systems, Revenue, By Product Type, 2017 (In %) Figure 116: Varian Medical Systems, Revenue, By Geographic Region, 2017 (In %) List of Tables Table A: Approach and Limitations of Common Treatment Modalities for Cancer Table B: Estimated number of proton therapy rooms needed worldwide Table C: Recent Company Acquisitions and Mergers in Proton Therapy Market Table D: Global Access to Healthcare Index, Ranking of Select Countries in Asia Pacific Region, 2017 (score out of 10)

IBA Proton Therapy Inc., Hitachi, Varian Medical Systems, Mevion Medical Systems, Advanced Oncotherapy plc, ProTom International, ProNova Solutions LLC and Sumitomo Heavy Industries, Ltd.