Table of Contents Table of Contents 3 List of Tables 5 List of Figures 5 Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Year, 2012 to YTD 2018 6 Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare Deals By Type, 2012 to YTD 2018 7 Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Region, 2012 to YTD 2018 8 Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Therapy Area, 2012 to YTD 2018 9 Sienna Biopharmaceuticals Inc, Medical Devices Deals, 2012 to YTD 2018 10 Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals Summary, 2012 to YTD 2018 11 Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare, Deal Details 12 Venture Financing 12 Sienna Biopharma Raises USD40 million in Series B Financing 12 Sienna Biopharma Raises Additional USD12 Million in Series A Financing 14 Sienna Biopharma Raises USD34 Million in Series A Financing 15 Sienna Biopharma Raises USD18.4 Million in Financing 16 Equity Offering 17 Sienna Biopharma Plans to Raise up to USD75 Million in Public Offering of Shares 17 Sienna Biopharma Raises USD74.7 Million in IPO 18 Sienna Biopharma Raises USD0.6 Million in Private Placement of Shares 20 Acquisition 21 Sienna Biopharmaceuticals Acquires Creabilis 21 Sienna Biopharmaceuticals Inc - Key Competitors 22 Sienna Biopharmaceuticals Inc - Key Employees 23 Sienna Biopharmaceuticals Inc - Locations And Subsidiaries 24 Head Office 24 Other Locations & Subsidiaries 24 Recent Developments 25 Financial Announcements 25 Aug 09, 2018: Sienna Biopharmaceuticals reports second quarter 2018 financial results 25 May 14, 2018: Sienna Biopharmaceuticals Reports First Quarter 2018 Financial Results 27 Mar 15, 2018: Sienna Biopharmaceuticals Reports Fourth Quarter and Full Year 2017 Financial Results 28 Nov 09, 2017: Sienna Biopharmaceuticals Reports Third Quarter 2017 Financial Results 30 Sep 07, 2017: Sienna Biopharmaceuticals Reports Second Quarter 2017 Financial Results 31 Corporate Communications 32 Aug 02, 2018: Sienna Biopharmaceuticals Appoints Finance Veteran, James M. Hindman, to Board of Directors 32 Mar 22, 2018: Sienna Biopharmaceuticals Appoints Caroline Van Hove as Chief Commercial Officer 33 Mar 21, 2018: Sienna Biopharmaceuticals Appoints John W. Smither as Chief Financial Officer 34 Jun 14, 2017: Sienna Biopharmaceuticals Appoints Erle Mast, Former CFO and Co-Founder of Clovis Oncology, to Board of Directors 35 Mar 24, 2017: Richard Peterson Joins Sienna Biopharmaceuticals As Chief Financial Officer 36 Legal and Regulatory 37 May 07, 2018: Sebacia Announces Favorable Ruling by U.S. Court of Appeals for the Federal Circuit Regarding Patent Interference Proceedings with Sienna Biopharmaceuticals 37 Product News 38 03/12/2018: Sienna Biopharmaceuticals Announces First Patient Dosed in Proof-of-Concept Trial of Topical by Design JAK Inhibitor SNA-125 for Atopic Dermatitis 38 02/14/2018: Sienna Biopharmaceuticals Announces First Patient Dosed in First-in-Human Trial of Topical SNA-125 39 Clinical Trials 40 Oct 24, 2017: Sienna Biopharmaceuticals Announces First Patient Dosed in Phase 2b Trial of Topical SNA-120 40 Appendix 41 Methodology 41 About 41 Contact Us 41 Disclaimer 41

List of Tables Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare, Key Facts, 2017 2 Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Year, 2012 to YTD 2018 6 Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare Deals By Type, 2012 to YTD 2018 7 Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Region, 2012 to YTD 2018 8 Sienna Biopharmaceuticals Inc, Deals By Therapy Area, 2012 to YTD 2018 9 Sienna Biopharmaceuticals Inc, Medical Devices Deals, 2012 to YTD 2018 10 Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals Summary, 2012 to YTD 2018 11 Sienna Biopharma Raises USD40 million in Series B Financing 12 Sienna Biopharma Raises Additional USD12 Million in Series A Financing 14 Sienna Biopharma Raises USD34 Million in Series A Financing 15 Sienna Biopharma Raises USD18.4 Million in Financing 16 Sienna Biopharma Plans to Raise up to USD75 Million in Public Offering of Shares 17 Sienna Biopharma Raises USD74.7 Million in IPO 18 Sienna Biopharma Raises USD0.6 Million in Private Placement of Shares 20 Sienna Biopharmaceuticals Acquires Creabilis 21 Sienna Biopharmaceuticals Inc, Key Competitors 22 Sienna Biopharmaceuticals Inc, Key Employees 23 Sienna Biopharmaceuticals Inc, Subsidiaries 24List of Figures Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals by Type, 2012 to YTD 2018 2 Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Year, 2012 to YTD 2018 2 Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Region, 2012 to YTD 2018 2 Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Therapy Area, 2012 to YTD 2018 2 Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Year, 2012 to YTD 2018 6 Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals by Type, 2012 to YTD 2018 7 Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Region, 2012 to YTD 2018 8 Sienna Biopharmaceuticals Inc, Pharmaceuticals & Healthcare, Deals By Therapy Area, 2012 to YTD 2018 9 Sienna Biopharmaceuticals Inc, Medical Devices Deals, 2012 to YTD 2018 10