1. Executive Summary 2. Research Methodology 3. Proton Therapy 3.1 Background 3.1.1 Types of Cancer Treatment 3.2 Overview 3.2.1 History of Proton Therapy 3.2.2 Benefits of Proton Therapy 3.2.3 Proton Therapy Devices 3.3 Proton Therapy – Technology 3.3.1 Pencil beam scanning systems 3.3.2 Uniform scanning systems 3.3.3 Passive scattering systems 4. Proton Therapy Market Analysis 4.1 Global Proton Therapy Market Sizing (Actual & Forecasted) 4.1.1 Global Proton Therapy Market Size by Value (Actual & Forecasted) 4.1.2 Global Proton Therapy Devices Market Size by Value (Actual & Forecasted) 4.1.3 Global Proton Therapy Capacity Gap 4.1.4 Global Proton Therapy Market Share by Product 4.1.5 Global Proton Therapy Market by Installed Base 4.1.6 Global Proton Therapy Facilities in Clinical Operation 4.1.7 Global Proton Therapy Market by New Treatment Rooms 4.1.8 Global Proton Therapy Market by Cumulative Treatment Rooms (Actual & Forecasted) 4.1.9 Global Proton Therapy Market by Patient Volume 5. Global Proton Therapy Market: Regional Analysis 5.1 North America 5.1.1 Proton Therapy Installed Base 5.1.2 Proton Therapy Facilities (Operational & Under-construction) 5.1.3 Patient Treatment Volume 5.2 Europe Proton Therapy Market 5.2.1 Proton Therapy Installed Base 5.2.2 Proton Therapy Facilities (Operational & Under-construction) 5.2.3 Patient Treatment Volume 5.3 Asia Proton Therapy Market 5.3.1 Proton Therapy Installed Base 5.3.2 Proton Therapy Facilities (Operational & Under-construction) 5.3.3 Patient Treatment Volume 6. Proton Therapy Market Dynamics 6.1 Industry Trends & Developments 6.1.1 Decreasing Cost of Proton Therapy Equipment 6.1.2 Technological Advancements in the Industry 6.2 Growth Drivers 6.2.1 Increasing Prevalence of Cancer 6.2.2 Growth in Geriatric Population 6.2.3 Minimally Invasive Nature 6.2.4 Rise in Public Awareness 6.3 Challenges 6.3.1 High Treatment Cost 6.3.2 Stringent Regulations 6.3.3 Limited Insurance Coverage 7. Competitive Landscape 7.1 Proton Therapy Systems Comparison 7.2 Market share by Competitors 7.2.1 Overall Market 7.2.2 Systems 7.2.3 Installed Base 7.2.4 Order Share 7.2.5 Market Share by Patients Treated 7.3 Market Share by Room Sales 7.3.1 Global 7.3.2 North America 7.3.3 The US 7.3.4 Japan 7.3.5 Rest of Asia Pacific 7.3.6 Europe, Middle East & Africa and Rest of World 8. Company Profiles 8.1 IBA Proton Therapy Inc. 8.1.1 Business Overview 8.1.2 Financial Overview 8.1.3 Business Strategies 8.2 Varian Medical Systems 8.2.1 Business Overview 8.2.2 Financial Overview 8.2.3 Business Strategies 8.3 Hitachi Ltd. 8.3.1 Business Overview 8.3.2 Financial Overview 8.3.3 Business Strategies 8.4 Mitsubishi Corporation 8.4.1 Business Overview 8.4.2 Financial Overview 8.4.3 Business Strategies

Figure 1: Rockville Research – Research Methodology Figure 2: Cancer Treatment Options Figure 3: Comparison of after-effects of Proton Therapy and X-ray Radiation on Prostate Cancer Patients Table 1: Risk of Secondary Cancer Development in Children post Radiation Therapy Table 2: Comparison of post-impact of Radiotherapy for Breast Cancer Patients Figure 4: Comparison to Results of Various Treatments for Lung Cancer Figure 5: Global Proton Therapy Market Size by Value, 2008-17E (US$ Millions) Figure 6: Global Proton Therapy Market Size by Value Forecasted, 2018E-22E (US$ Millions) Figure 7: Global Proton Therapy Devices Market Size by Value, 2008-17E (US$ Millions) Figure 8: Global Proton Therapy Devices Market Size by Value Forecasted, 2018E-22E (US$ Millions) Figure 9: Global Proton Therapy Capacity Gap (2017 & 2035) Figure 10: Global Proton Therapy Market Share by Product (Equipment & Services), 2014-22E Figure 11: Global Proton Therapy Market by Installed Base (2016) Figure 12: Global Proton Therapy Facilities in Operation, 2010-17E (Units) Figure 13: Global Proton Therapy Market by Cumulative Treatment Rooms, 2008-17E (Units) Figure 14: Global Proton Therapy Market by Cumulative Treatment Rooms Forecasted, 2018E-22E (Units) Figure 15: Global Proton Therapy Market by Patient Volume, 2008-17E (Units) Table 3: Number of Proton Therapy Centers and Treatment Rooms by Region Figure 16: Density of Proton Therapy Centers and Treatment Rooms by Region, 2016 (per 100 million population) Figure 17: North America Proton Therapy Market by Installed Base (2016) Table 4: North America - Proton Therapy Facilities in Operation (Till 2016) Table 5: North America - Proton Therapy Facilities Under-Construction Table 6: North America - Proton Therapy Facilities in Planning Stage Figure 18: North America - Proton Therapy Patients Treatment Cumulative Volume; 2008-2017E Figure 19: Europe Proton Therapy Market by Installed Base (2017E) Table 7: Europe - Proton Therapy Facilities in Operation (Till 2016) Table 8: Europe - Proton Therapy Facilities Under-Construction (Till 2016) Table 9: Europe - Proton Therapy Facilities in Planning Stage Figure 20: Europe & Russia - Proton Therapy Patients Treatment Cumulative Volume; 2008-2017E Figure 21: Asia - Proton Therapy Market by Installed Base; 2010-2015E (Units) Table 10: Asia - Proton Therapy Facilities in Operation (Till 2016) Table 11: Asia - Proton Therapy Facilities Under-Construction Table 12: Asia Proton Therapy Facilities in Planning Stage Figure 22: Asia - Proton Therapy Patients Treatment Cumulative Volume; 2008-2015 Table 13: Incidence of Common Types of Cancer and Estimated Deaths (2016) Figure 23: Average Number of Cancer Cases per Year and Age-Specific Incidence Rates, 2010-17 Figure 24: Global Geriatric Population, 2008-17 (Millions) Table 14: FDA Regulation of Medical Devices Table 15: Proton Therapy Systems Competitive Landscape Figure 25: Global Proton Therapy Market Share by Competitors, 2015-18E Figure 26: Global Proton Therapy Installed Base Market Share by Systems (2017) Figure 27: Global Proton Therapy Installed Base Market Share by Competitors (2016E) Figure 28: Global Proton Therapy Device Orders Market Share by Competitors (2015) Figure 29: Global Proton Therapy Players Market Share by Patients (2017) Figure 30: Global Proton Therapy Market Share by Installed Base of Room (2017) Figure 31: North America Proton Therapy Market Share by Facilities (till Sept’16) Figure 32: North America Proton Therapy Market Share by Room Sales (till Sept’16) Figure 33: North America Proton Therapy Market Share by Room Type (till Sept’16) Figure 34: The US Proton Therapy Market Share by Number of Centers (till Sept’16) Figure 35: The US Proton Therapy Market Share by Number of Rooms (till Sept’16) Figure 36: Japan Proton Therapy Market Share by Number of Rooms (till Nov’16) Figure 37: Rest of APAC Proton Therapy Market Share by Number of Rooms (till Nov’16) Figure 38: EMEA & RoW Proton Therapy Market Share by Number of Rooms (till Nov’16) Figure 39: IBA Proton Therapy Revenue by Business Segment (FY2017) Figure 40: IBA Proton Therapy Revenue, FY2011-FY2016 (US$ Millions) Figure 41: Varian Medical Systems Revenue by Business Segment (FY2016) Figure 42: Varian Medical Systems Revenue, FY2011-FY2016 (US$ Billions) Figure 43: Hitachi Ltd. Revenue by Business Segment (FY2016) Figure 44: Hitachi Ltd. Revenue, FY2011-FY2016 (US$ Millions) Figure 45: Mitsubishi Corporation Revenue by Business Segment (FY2017) Figure 46: Mitsubishi Corporation Net Sales, FY2011-FY2017 (US$ Millions)

IBA Proton Therapy Inc, Varian Medical Systems, Hitachi Limited, Mitsubishi Corporation