PART 01: EXECUTIVE SUMMARY PART 02: SCOPE OF THE REPORT PART 03: RESEARCH METHODOLOGY PART 04: MARKET LANDSCAPE • Market ecosystem • Market characteristics • Market segmentation analysis PART 05: MARKET SIZING • Market definition • Market sizing 2017 • Market size and forecast 2017-2022 PART 06: FIVE FORCES ANALYSIS • Bargaining power of buyers • Bargaining power of suppliers • Threat of new entrants • Threat of substitutes • Threat of rivalry • Market condition PART 07: MARKET SEGMENTATION BY PRODUCT • Segmentation by product • Comparison by product • TMV – Market size and forecast 2017-2022 • TAV – Market size and forecast 2017-2022 • Market opportunity by product PART 08: CUSTOMER LANDSCAPE PART 09: MARKET SEGMENTATION BY END-USER • Segmentation by end-user • Hospitals • ASCs • Specialty cardiac centers PART 10: REGIONAL LANDSCAPE • Geographical segmentation • Regional comparison • Americas – Market size and forecast 2017-2022 • EMEA – Market size and forecast 2017-2022 • APAC – Market size and forecast 2017-2022 • Market opportunity PART 11: DECISION FRAMEWORK PART 12: DRIVERS AND CHALLENGES • Market drivers • Market challenges PART 13: MARKET TRENDS • New product launches coupled with R&D activities • Advances in technology • Increase in M&A • Emergence of two-in-one valve solutions PART 14: VENDOR LANDSCAPE • Overview • Landscape disruption • Competitive landscape PART 15: VENDOR ANALYSIS • Vendors covered • Vendor classification • Market positioning of vendors • Edwards Lifesciences • Medtronic • Boston Scientific • Abbott • Lepu Medical Technology PART 16: APPENDIX • List of abbreviations Exhibit 01: Parent market Exhibit 02: Global cardiac prosthetic devices market Exhibit 03: Market characteristics Exhibit 04: Market segments Exhibit 05: Types of surgical techniques for valvular diseases Exhibit 06: Market definition - Inclusions and exclusions checklist Exhibit 07: Market size 2017 Exhibit 08: Validation techniques employed for market sizing 2017 Exhibit 09: Global – Market size and forecast 2017-2022 ($ mn) Exhibit 10: Global – Year-over-year growth 2018-2022 (%) Exhibit 11: Five forces analysis 2017 Exhibit 12: Five forces analysis 2022 Exhibit 13: Bargaining power of buyers Exhibit 14: Bargaining power of suppliers Exhibit 15: Threat of new entrants Exhibit 16: Threat of substitutes Exhibit 17: Threat of rivalry Exhibit 18: Market condition - Five forces 2017 Exhibit 19: Product – Market share 2017-2022 (%) Exhibit 20: Comparison by product Exhibit 21: TMV – Market size and forecast 2017-2022 ($ mn) Exhibit 22: TMV – Year-over-year growth 2018-2022 (%) Exhibit 23: TAV – Market size and forecast 2017-2022 ($ mn) Exhibit 24: TAV – Year-over-year growth 2018-2022 (%) Exhibit 25: Market opportunity by product Exhibit 26: Customer landscape Exhibit 27: End-user – Market share 2017 (%) Exhibit 28: Global – Market share by geography 2017-2022 (%) Exhibit 29: Regional comparison Exhibit 30: Americas – Market size and forecast 2017-2022 ($ mn) Exhibit 31: Americas – Year-over-year growth 2018-2022 (%) Exhibit 32: Top three countries in Americas Exhibit 33: EMEA – Market size and forecast 2017-2022 ($ mn) Exhibit 34: EMEA – Year-over-year growth 2018-2022 (%) Exhibit 35: Top three countries in EMEA Exhibit 36: APAC – Market size and forecast 2017-2022 ($ mn) Exhibit 37: APAC – Year-over-year growth 2018-2022 (%) Exhibit 38: Top three countries in APAC Exhibit 39: Market opportunity Exhibit 40: Product recalls 2015-2017 Exhibit 41: New product launches in 2016 – 2017 Exhibit 42: Major M&A deals during 2015–2017 Exhibit 43: Vendor landscape Exhibit 44: Landscape disruption Exhibit 45: Top vendors in global transcatheter heart valves market 2017 Exhibit 46: Vendors covered Exhibit 47: Vendor classification Exhibit 48: Market positioning of vendors Exhibit 49: Edwards Lifesciences: Overview Exhibit 50: Edwards Lifesciences – Business segments Exhibit 51: Edwards Lifesciences – Organizational developments Exhibit 52: Edwards Lifesciences – Geographic focus Exhibit 53: Edwards Lifesciences – Segment focus Exhibit 54: Edwards Lifesciences – Key offerings Exhibit 55: Edwards Lifesciences – Key customers Exhibit 56: Medtronic: Overview Exhibit 57: Medtronic: Business segments Exhibit 58: Medtronic: Organizational developments Exhibit 59: Medtronic: Geographic focus Exhibit 60: Medtronic: Segment focus Exhibit 61: Medtronic: Key offerings Exhibit 62: Medtronic: Key customers Exhibit 63: Boston Scientific: Overview Exhibit 64: Boston Scientific – Business segments Exhibit 65: Boston Scientific – Organizational developments Exhibit 66: Boston Scientific – Geographic focus Exhibit 67: Boston Scientific – Segment focus Exhibit 68: Boston Scientific – Key offerings Exhibit 69: Boston Scientific – Key customers Exhibit 70: Abbott: Overview Exhibit 71: Abbott – Business segments Exhibit 72: Abbott – Organizational developments Exhibit 73: Abbott – Geographic focus Exhibit 74: Abbott – Segment focus Exhibit 75: Abbott – Key offerings Exhibit 76: Abbott – Key customers Exhibit 77: Lepu Medical Technology: Overview Exhibit 78: Lepu Medical Technology – Products categories Exhibit 79: Lepu Medical Technology – Organizational developments Exhibit 80: Lepu Medical Technology – Geographic focus Exhibit 81: Lepu Medical Technology – Segment focus Exhibit 82: Lepu Medical Technology – Key offerings Exhibit 83: Lepu Medical Technology – Key customers

Edwards Lifesciences Medtronic Boston Scientific Abbott Lepu Medical Technology