1 Table of Contents 1 Table of Contents 4 1.1 List of Tables 5 1.2 List of Figures 6 2 Introduction 7 2.1 Fungal Foot Infections Report Coverage 7 2.2 Onychomycosis (Tinea Unguium) - Overview 7 2.3 Tinea pedis (Athlete Foot) - Overview 7 3 Therapeutics Development 8 3.1 Onychomycosis (Tinea Unguium) 8 3.2 Tinea pedis (Athlete Foot) 12 4 Therapeutics Assessment 15 4.1 Onychomycosis (Tinea Unguium) 15 4.2 Tinea pedis (Athlete Foot) 21 5 Companies Involved in Therapeutics Development 26 5.1 Onychomycosis (Tinea Unguium) 26 5.2 Tinea pedis (Athlete Foot) 32 6 Dormant Projects 36 6.1 Onychomycosis (Tinea Unguium) 36 6.2 Tinea pedis (Athlete Foot) 38 7 Discontinued Products 39 7.1 Onychomycosis (Tinea Unguium) 39 8 Product Development Milestones 40 8.1 Onychomycosis (Tinea Unguium) 40 8.2 Tinea pedis (Athlete Foot) 50 9 Appendix 57 9.1 Methodology 57 9.2 Coverage 57 9.3 Secondary Research 57 9.4 Primary Research 57 9.5 Expert Panel Validation 57 9.6 Contact Us 58 9.7 Disclaimer 58

1.1 List of Tables Table 1: Number of Products under Development for Onychomycosis (Tinea Unguium) 8 Table 2: Number of Products under Development by Companies, Onychomycosis (Tinea Unguium) 10 Table 3: Products under Development by Companies, Onychomycosis (Tinea Unguium) 11 Table 4: Number of Products under Development for Tinea pedis (Athlete Foot) 12 Table 5: Number of Products under Development by Companies, Tinea pedis (Athlete Foot) 13 Table 6: Products under Development by Companies, Tinea pedis (Athlete Foot) 14 Table 7: Number of Products by Stage and Target, Onychomycosis (Tinea Unguium) 16 Table 8: Number of Products by Stage and Mechanism of Action, Onychomycosis (Tinea Unguium) 17 Table 9: Number of Products by Stage and Route of Administration, Onychomycosis (Tinea Unguium) 19 Table 10: Number of Products by Stage and Molecule Type, Onychomycosis (Tinea Unguium) 20 Table 11: Number of Products by Stage and Target, Tinea pedis (Athlete Foot) 22 Table 12: Number of Products by Stage and Mechanism of Action, Tinea pedis (Athlete Foot) 23 Table 13: Number of Products by Stage and Route of Administration, Tinea pedis (Athlete Foot) 25 Table 14: Number of Products by Stage and Molecule Type, Tinea pedis (Athlete Foot) 25 Table 15: Onychomycosis (Tinea Unguium) - Pipeline by Almirall SA 26 Table 16: Onychomycosis (Tinea Unguium) - Pipeline by Blueberry Therapeutics Ltd 27 Table 17: Onychomycosis (Tinea Unguium) - Pipeline by Dermala Inc 27 Table 18: Onychomycosis (Tinea Unguium) - Pipeline by Eisai Co Ltd 27 Table 19: Onychomycosis (Tinea Unguium) - Pipeline by Helix BioMedix Inc 28 Table 20: Onychomycosis (Tinea Unguium) - Pipeline by Hexima Ltd 28 Table 21: Onychomycosis (Tinea Unguium) - Pipeline by Kaken Pharmaceutical Co Ltd 29 Table 22: Onychomycosis (Tinea Unguium) - Pipeline by Meiji Seika Pharma Co Ltd 29 Table 23: Onychomycosis (Tinea Unguium) - Pipeline by Moberg Pharma AB 30 Table 24: Onychomycosis (Tinea Unguium) - Pipeline by NAL Pharmaceuticals Ltd 30 Table 25: Onychomycosis (Tinea Unguium) - Pipeline by Novabiotics Ltd 31 Table 26: Onychomycosis (Tinea Unguium) - Pipeline by Novan Inc 31 Table 27: Onychomycosis (Tinea Unguium) - Pipeline by Viamet Pharmaceuticals Inc 32 Table 28: Tinea pedis (Athlete Foot) - Pipeline by Astellas Pharma Inc 32 Table 29: Tinea pedis (Athlete Foot) - Pipeline by Biolab Farmaceutica Ltda 33 Table 30: Tinea pedis (Athlete Foot) - Pipeline by Blueberry Therapeutics Ltd 33 Table 31: Tinea pedis (Athlete Foot) - Pipeline by Broda Tech LLC 34 Table 32: Tinea pedis (Athlete Foot) - Pipeline by Novan Inc 34 Table 33: Tinea pedis (Athlete Foot) - Pipeline by Novoteris LLC 35 Table 34: Tinea pedis (Athlete Foot) - Pipeline by Sanotize Research And Development Corp 35 Table 35: Tinea pedis (Athlete Foot) - Pipeline by Viamet Pharmaceuticals Inc 35 Table 36: Onychomycosis (Tinea Unguium) - Dormant Projects 36 Table 37: Tinea pedis (Athlete Foot) - Dormant Projects 38 Table 38: Onychomycosis (Tinea Unguium) - Discontinued Products 39 1.2 List of Figures Figure 1: Number of Products under Development for Onychomycosis (Tinea Unguium) 8 Figure 2: Number of Products under Development by Companies, Onychomycosis (Tinea Unguium) 9 Figure 3: Number of Products under Development for Tinea pedis (Athlete Foot) 12 Figure 4: Number of Products under Development by Companies, Tinea pedis (Athlete Foot) 13 Figure 5: Number of Products by Targets, Onychomycosis (Tinea Unguium) 15 Figure 6: Number of Products by Stage and Targets, Onychomycosis (Tinea Unguium) 15 Figure 7: Number of Products by Mechanism of Actions, Onychomycosis (Tinea Unguium) 16 Figure 8: Number of Products by Stage and Mechanism of Actions, Onychomycosis (Tinea Unguium) 17 Figure 9: Number of Products by Routes of Administration, Onychomycosis (Tinea Unguium) 18 Figure 10: Number of Products by Stage and Routes of Administration, Onychomycosis (Tinea Unguium) 18 Figure 11: Number of Products by Molecule Types, Onychomycosis (Tinea Unguium) 19 Figure 12: Number of Products by Stage and Molecule Types, Onychomycosis (Tinea Unguium) 20 Figure 13: Number of Products by Targets, Tinea pedis (Athlete Foot) 21 Figure 14: Number of Products by Stage and Targets, Tinea pedis (Athlete Foot) 21 Figure 15: Number of Products by Mechanism of Actions, Tinea pedis (Athlete Foot) 22 Figure 16: Number of Products by Stage and Mechanism of Actions, Tinea pedis (Athlete Foot) 23 Figure 17: Number of Products by Routes of Administration, Tinea pedis (Athlete Foot) 24 Figure 18: Number of Products by Stage and Routes of Administration, Tinea pedis (Athlete Foot) 24 Figure 19: Number of Products by Stage and Molecule Types, Tinea pedis (Athlete Foot) 25

Almirall SA Astellas Pharma Inc Biolab Farmaceutica Ltda Blueberry Therapeutics Ltd Broda Tech LLC Dermala Inc Eisai Co Ltd Helix BioMedix Inc Hexima Ltd Kaken Pharmaceutical Co Ltd Meiji Seika Pharma Co Ltd Moberg Pharma AB NAL Pharmaceuticals Ltd Novabiotics Ltd Novan Inc Novoteris LLC Onychomycosis (Tinea Unguium) Sanotize Research And Development Corp Tinea pedis (Athlete Foot) Viamet Pharmaceuticals Inc