Table of Contents Table of Contents 2 Introduction 5 Dyskinesia - Overview 6 Dyskinesia - Therapeutics Development 7 Dyskinesia - Therapeutics Assessment 16 Dyskinesia - Companies Involved in Therapeutics Development 25 Dyskinesia - Drug Profiles 35 Dyskinesia - Dormant Projects 141 Dyskinesia - Discontinued Products 143 Dyskinesia - Product Development Milestones 144 Appendix 154

List of Tables Number of Products under Development for Dyskinesia, H1 2018 Number of Products under Development by Companies, H1 2018 Number of Products under Development by Companies, H1 2018 (Contd..1), H1 2018 Number of Products under Development by Universities/Institutes, H1 2018 Products under Development by Companies, H1 2018 Products under Development by Companies, H1 2018 (Contd..1), H1 2018 Products under Development by Companies, H1 2018 (Contd..2), H1 2018 Products under Development by Universities/Institutes, H1 2018 Number of Products by Stage and Target, H1 2018 Number of Products by Stage and Mechanism of Action, H1 2018 Number of Products by Stage and Mechanism of Action, H1 2018 (Contd..1), H1 2018 Number of Products by Stage and Route of Administration, H1 2018 Number of Products by Stage and Molecule Type, H1 2018 Dyskinesia - Pipeline by Adamas Pharmaceuticals Inc, H1 2018 Dyskinesia - Pipeline by Addex Therapeutics Ltd, H1 2018 Dyskinesia - Pipeline by Advicenne SA, H1 2018 Dyskinesia - Pipeline by Amarantus Bioscience Holdings Inc, H1 2018 Dyskinesia - Pipeline by Avanir Pharmaceuticals Inc, H1 2018 Dyskinesia - Pipeline by Bionomics Ltd, H1 2018 Dyskinesia - Pipeline by Cadent Therapeutics, H1 2018 Dyskinesia - Pipeline by Cavion LLC, H1 2018 Dyskinesia - Pipeline by Clevexel Pharma SAS, H1 2018 Dyskinesia - Pipeline by EpiVax Inc, H1 2018 Dyskinesia - Pipeline by Heptares Therapeutics Ltd, H1 2018 Dyskinesia - Pipeline by Ipsen SA, H1 2018 Dyskinesia - Pipeline by IRLAB Therapeutics AB, H1 2018 Dyskinesia - Pipeline by Medy-Tox Inc, H1 2018 Dyskinesia - Pipeline by Merz Pharma GmbH & Co KgaA, H1 2018 Dyskinesia - Pipeline by Neurim Pharmaceuticals Ltd, H1 2018 Dyskinesia - Pipeline by Neurocrine Biosciences Inc, H1 2018 Dyskinesia - Pipeline by Neurolixis Inc, H1 2018 Dyskinesia - Pipeline by Phenomenome Discoveries Inc, H1 2018 Dyskinesia - Pipeline by Sage Therapeutics Inc, H1 2018 Dyskinesia - Pipeline by SciFluor Life Sciences LLC, H1 2018 Dyskinesia - Pipeline by SOM Biotech SL, H1 2018 Dyskinesia - Pipeline by Synchroneuron Inc, H1 2018 Dyskinesia - Dormant Projects, H1 2018 Dyskinesia - Dormant Projects, H1 2018 (Contd..1), H1 2018 Dyskinesia - Discontinued Products, H1 2018List of Figures Number of Products under Development for Dyskinesia, H1 2018 Number of Products under Development by Companies, H1 2018 Number of Products under Development by Universities/Institutes, H1 2018 Number of Products by Top 10 Targets, H1 2018 Number of Products by Stage and Top 10 Targets, H1 2018 Number of Products by Top 10 Mechanism of Actions, H1 2018 Number of Products by Stage and Top 10 Mechanism of Actions, H1 2018 Number of Products by Routes of Administration, H1 2018 Number of Products by Stage and Routes of Administration, H1 2018 Number of Products by Molecule Types, H1 2018 Number of Products by Stage and Molecule Types, H1 2018