1. Executive Summary 2. Japan Proton Therapy Market Analysis 2.1 Japan Proton Therapy - Actual and Potential Market (2003 - 2022) 2.1.1 Japan - Actual Proton Therapy Market and Forecast 2.1.2 Japan - Potential Proton Therapy Market and Forecast 2.2 Japan Proton Therapy Patients Number - Actual and Potential (2003 - 2022) 2.2.1 Japan - Patients Treated with Proton Therapy Actual Number and Forecast 2.2.2 Japan - Potential Candidate for Proton Therapy Number and Forecast 3. Japan - List of Proton Therapy Centers, Cost, Start of Treatment, Patient Treated 4. Japan Proton Therapy - Company Analysis 4.1 The Proton Therapy Centers Developed by Mitsubishi 4.2 The Proton Therapy Centers Developed by IBA 4.3 The Proton Therapy Centers Developed by Hitachi 4.4 The Proton Therapy Centers Developed by Sumitomo Heavy Industries 5. Japan – Number of Patients Treated at Proton Therapy Centers 5.1 National Institute of Radiological Sciences - Number of Patients Treated (2008 – 2015) 5.2 Hyogo Ion Beam Medical Center - Number of Patients Treated (2007 – 2015) 5.3 Shizuoka Cancer Center - Number of Patients Treated (2007 – 2015) 5.4 Southern Tohoku Proton Therapy Center - Number of Patients Treated (2013 – 2014) 5.5 Gunma University Heavy Ion Medical Center - Number of Patients Treated (2013 – 2015) 5.6 Fukui Prefectural Hospital Proton Beam Cancer Treatment Center - Number of Patients Treated (2013 – 2015) 5.7 Medipolis Medical Research Institute - Number of Patients Treated (2013 – 2015) 5.8 Saga Heavy Ion Medical Accelerator in Tosu - Number of Patients Treated (2013 – 2015) 5.9 Japanese National Cancer Center - Number of Patients Treated (2007 – 2014) 5.10 The Proton Medical Research Center 2, University of Tsukuba, JAPAN - Number of Patients Treated (2007 – 2015) 5.11 Nagoya City Quality Life 21 Jouhoku, Japan - Number of Patients Treated (2013 – 2015) 5.12 Aizawa Hospital - Number of Patients Treated (Oct - 2014) 6. Current Radiation Therapies 6.1 Third Dimensional Conformal Therapy (CRT) 6.2 Image Guided Radiotherapy (IGRT) 6.3 Intensity Modulated Radiotherapy (IMRT) 6.4 Stereotactic Radiotherapy 6.5 Neutron Therapy 6.6 Heavy Ion Radiotherapy 6.7 Proton Therapy 7. Components of a Standard Proton Therapy Center 7.1 Proton Accelerator 7.2 Beam Transport System 7.3 Beam Delivery System 7.3.1 The Passive Scattering Technique 7.3.2 Beam Scanning 7.4 Nozzle 7.4.1 Single Scattering 7.4.2 Double Scattering 7.4.3 Uniform Scanning Nozzle 7.4.4 Pencil Scanning Nozzle 7.5 Treatment Planning System 7.6 Image Viewers 7.7 Patient Positioning System (PPS) 7.8 Human Resource 8. Proton Therapy - Driving Factors 8.1 Technology Advancement 8.1.1 Next-Generation Proton Technique 8.1.2 Technological Advances Make Proton Therapy Centers More Scalable 8.2 Growing Incidence of Cancer Patients 8.3 Proton Therapy Provides Enormous Benefits 9. Proton Therapy - Challenges 9.1 Requires Huge Investment 9.2 Operations Challenges 9.3 More Clinical Evidence Is Needed

List of Figures: Figure 2-1: Japan – Actual Proton Therapy Market (Million US$), 2003 - 2016 Figure 2-2: Japan - Forecast for Actual Proton Therapy Market (Million US$), 2017 - 2022 Figure 2-3: Japan - Potential Proton Therapy Market (Million US$), 2005 - 2016 Figure 2-4: Japan - Forecast for Potential Proton Therapy Market (Million US$), 2017 - 2022 Figure 2-5: Japan - Patient Treated with Proton Therapy (Number), 2003 - 2016 Figure 2-6: Japan - Forecast for Patient Treated with Proton Therapy (Number), 2017 - 2022 Figure 2-7: Japan - Potential Candidate for Proton Therapy (Number), 2005 - 2016 Figure 2-8: Japan - Forecast for Potential Candidate for Proton Therapy (Number), 2017 - 2022 Figure 5-1: National Institute of Radiological Sciences - Total Patients Treated (Number), 2008 – 2015 Figure 5-2: Hyogo Ion Beam Medical Center - Total Patients Treated (Number), 2007 – 2015 Figure 5-3: Shizuoka Cancer Center - Total Patients Treated (Number), 2007 – 2015 Figure 5-4: Southern Tohoku Proton Therapy Center - Total Patients Treated (Number), 2013 – 2014 Figure 5-5: Gunma University Heavy Ion Medical Center - Total Patients Treated (Number), 2013 – 2015 Figure 5-6: Fukui Prefectural Hospital Proton Beam Cancer Treatment Center - Total Patients Treated (Number), 2013 – 2015 Figure 5-7: Medipolis Medical Research Institute - Total Patients Treated (Number), 2013 – 2015 Figure 5-8: Saga Heavy Ion Medical Accelerator in Tosu - Total Patients Treated (Number), 2013 – 2015 Figure 5-9: Japanese National Cancer Center - Total Patients Treated (Number), 2007 – 2014 Figure 5-10: The Proton Medical Research Center 2, University of Tsukuba - Total Patients Treated (Number), 2007 – 2015 Figure 5-11: Nagoya City Quality Life 21 Jouhoku - Total Patients Treated (Number), 2013 – 2015 Figure 8-1: Japan - Number of Patient Diagnosed with Cancer (Number), 2009 - 2016 Figure 8-2: Japan - Forecast for Number of Patient Diagnosed with Cancer (Number), 2017 - 2022 List of Tables: Table 3-1: Japan - List of Proton Therapy Centers Operational, Under Construction and Planned Table 4-1: Japan - Mitsubishi Proton Therapy Centers Operational and Planned Table 4-2: Japan - IBA Proton Therapy Centers Operational and Planned Table 4-3: Japan - Hitachi Proton Therapy Centers Operational and Planned Table 4-4: Japan - Sumitomo Operational Proton Therapy Centers