Table of Contents List of Tables List of Figures Introduction Global Markets Direct Report Coverage Degenerative Disc Disease - Overview Degenerative Disc Disease - Therapeutics Development Pipeline Overview Pipeline by Companies Products under Development by Companies Degenerative Disc Disease - Therapeutics Assessment Assessment by Target Assessment by Mechanism of Action Assessment by Route of Administration Assessment by Molecule Type Degenerative Disc Disease - Companies Involved in Therapeutics Development AnGes MG Inc Biopharm GmbH BioRestorative Therapies Inc Bone Therapeutics SA DiscGenics Inc Osiris Therapeutics Inc Samumed LLC TissueGene Inc U.S. Stem Cell Inc Yuhan Corp Degenerative Disc Disease - Drug Profiles AdipoCell - Drug Profile Product Description Mechanism Of Action R&D Progress ALLOB - Drug Profile Product Description Mechanism Of Action R&D Progress AMG-0101 - Drug Profile Product Description Mechanism Of Action R&D Progress AMG-0103 - Drug Profile Product Description Mechanism Of Action R&D Progress BRTX-100 - Drug Profile Product Description Mechanism Of Action R&D Progress OTICR-01 - Drug Profile Product Description Mechanism Of Action R&D Progress Recombinant Protein for Bone Fracture, Degenerative Disc Disease, Erectile Dysfunction and Parkinson's Disease - Drug Profile Product Description Mechanism Of Action R&D Progress SM-04690 - Drug Profile Product Description Mechanism Of Action R&D Progress Small Molecule for Degenerative Disc Disease - Drug Profile Product Description Mechanism Of Action R&D Progress Stem Cell Therapy for Degenerative Disc Disease - Drug Profile Product Description Mechanism Of Action R&D Progress TG-D - Drug Profile Product Description Mechanism Of Action R&D Progress X-0002 - Drug Profile Product Description Mechanism Of Action R&D Progress YH-14618 - Drug Profile Product Description Mechanism Of Action R&D Progress Degenerative Disc Disease - Dormant Projects Degenerative Disc Disease - Product Development Milestones Featured News & Press Releases Jan 15, 2018: USRM Reaches Key Sales Milestone of Proprietary Adipocell Product Dec 18, 2017: Samumed Doses First Patient in Phase I Trial of SM04690 for Treatment of Degenerative Disc Disease Nov 28, 2017: Degenerative Disc Patients Significantly Improve With USRM’s Adipocell Oct 05, 2017: BioRestorative Therapies Announces Published Study of Licensed Technology to Treat Lumbar Degenerative Disc Disease Oct 03, 2017: DiscGenics Receives FDA Allowance of IND to Commence Clinical Study of its Degenerative Disc Disease Therapy Mar 09, 2017: Bone Therapeutics Completes Recruitment of 16 Patients in ALLOB PHASE I/IIA Delayed-Union Study Feb 08, 2017: BioRestorative Therapies Receives FDA Clearance to Initiate Phase 2 Clinical Trial for the Treatment of Patients with Degenerative Disc Disease Jan 09, 2017: BioRestorative Therapies Submits IND Application to FDA to Treat Patients with Degenerative Disc Disease Nov 15, 2016: Samumed Presents Data for a

List of Tables Number of Products under Development for Degenerative Disc Disease, H1 2018 Number of Products under Development by Companies, H1 2018 Products under Development by Companies, H1 2018 Number of Products by Stage and Target, H1 2018 Number of Products by Stage and Mechanism of Action, H1 2018 Number of Products by Stage and Route of Administration, H1 2018 Number of Products by Stage and Molecule Type, H1 2018 Degenerative Disc Disease - Pipeline by AnGes MG Inc, H1 2018 Degenerative Disc Disease - Pipeline by Biopharm GmbH, H1 2018 Degenerative Disc Disease - Pipeline by BioRestorative Therapies Inc, H1 2018 Degenerative Disc Disease - Pipeline by Bone Therapeutics SA, H1 2018 Degenerative Disc Disease - Pipeline by DiscGenics Inc, H1 2018 Degenerative Disc Disease - Pipeline by Osiris Therapeutics Inc, H1 2018 Degenerative Disc Disease - Pipeline by Samumed LLC, H1 2018 Degenerative Disc Disease - Pipeline by TissueGene Inc, H1 2018 Degenerative Disc Disease - Pipeline by U.S. Stem Cell Inc, H1 2018 Degenerative Disc Disease - Pipeline by Yuhan Corp, H1 2018 Degenerative Disc Disease - Dormant Projects, H1 2018 List of Figures Number of Products under Development for Degenerative Disc Disease, H1 2018 Number of Products under Development by Companies, H1 2018 Number of Products by Targets, H1 2018 Number of Products by Stage and Targets, H1 2018 Number of Products by Mechanism of Actions, H1 2018 Number of Products by Stage and Mechanism of Actions, H1 2018 Number of Products by Routes of Administration, H1 2018 Number of Products by Stage and Routes of Administration, H1 2018 Number of Products by Molecule Types, H1 2018 Number of Products by Stage and Molecule Types, H1 2018

AnGes MG Inc Biopharm GmbH BioRestorative Therapies Inc Bone Therapeutics SA DiscGenics Inc Osiris Therapeutics Inc Samumed LLC TissueGene Inc U.S. Stem Cell Inc Yuhan Corp