Table of Contents Table of Contents 2 List of Tables 3 List of Figures 4 Introduction 5 Global Markets Direct Report Coverage 5 Wilms' Tumor (Nephroblastoma) Overview 6 Therapeutics Development 7 Pipeline Products for Wilms' Tumor (Nephroblastoma) - Overview 7 Pipeline Products for Wilms' Tumor (Nephroblastoma) - Comparative Analysis 8 Wilms' Tumor (Nephroblastoma) - Therapeutics under Development by Companies 9 Wilms' Tumor (Nephroblastoma) - Therapeutics under Investigation by Universities/Institutes 10 Wilms' Tumor (Nephroblastoma) - Pipeline Products Glance 11 Clinical Stage Products 11 Early Stage Products 12 Wilms' Tumor (Nephroblastoma) - Products under Development by Companies 13 Wilms' Tumor (Nephroblastoma) - Products under Investigation by Universities/Institutes 14 Wilms' Tumor (Nephroblastoma) - Companies Involved in Therapeutics Development 15 Exelixis Inc 15 NanoSmart Pharmaceuticals Inc 16 Recombio SL 17 Selvita SA 18 Wilms' Tumor (Nephroblastoma) - Therapeutics Assessment 19 Assessment by Monotherapy Products 19 Assessment by Target 20 Assessment by Mechanism of Action 22 Assessment by Route of Administration 24 Assessment by Molecule Type 26 Drug Profiles 28 cabozantinib s-malate - Drug Profile 28 Product Description 28 Mechanism Of Action 28 R&D Progress 28 Cellular Immunotherapy for Oncology - Drug Profile 44 Product Description 44 Mechanism Of Action 44 R&D Progress 44 Monoclonal Antibody Conjugate for Wilms' Tumor - Drug Profile 46 Product Description 46 Mechanism Of Action 46 R&D Progress 46 Monoclonal Antibody Conjugate to Target B7-H3 for Oncology - Drug Profile 47 Product Description 47 Mechanism Of Action 47 R&D Progress 47 racotumomab - Drug Profile 48 Product Description 48 Mechanism Of Action 48 R&D Progress 48 SEL-12034 - Drug Profile 50 Product Description 50 Mechanism Of Action 50 R&D Progress 50 Wilms' Tumor (Nephroblastoma) - Dormant Projects 52 Appendix 53 Methodology 53 Coverage 53 Secondary Research 53 Primary Research 53 Expert Panel Validation 53 Contact Us 53 Disclaimer 54

List of Tables Number of Products under Development for Wilms' Tumor (Nephroblastoma), H2 2016 7 Number of Products under Development for Wilms' Tumor (Nephroblastoma) - Comparative Analysis, H2 2016 8 Number of Products under Development by Companies, H2 2016 9 Number of Products under Investigation by Universities/Institutes, H2 2016 10 Comparative Analysis by Clinical Stage Development, H2 2016 11 Comparative Analysis by Early Stage Development, H2 2016 12 Products under Development by Companies, H2 2016 13 Products under Investigation by Universities/Institutes, H2 2016 14 Wilms' Tumor (Nephroblastoma) - Pipeline by Exelixis Inc, H2 2016 15 Wilms' Tumor (Nephroblastoma) - Pipeline by NanoSmart Pharmaceuticals Inc, H2 2016 16 Wilms' Tumor (Nephroblastoma) - Pipeline by Recombio SL, H2 2016 17 Wilms' Tumor (Nephroblastoma) - Pipeline by Selvita SA, H2 2016 18 Assessment by Monotherapy Products, H2 2016 19 Number of Products by Stage and Target, H2 2016 21 Number of Products by Stage and Mechanism of Action, H2 2016 23 Number of Products by Stage and Route of Administration, H2 2016 25 Number of Products by Stage and Molecule Type, H2 2016 27 Wilms' Tumor (Nephroblastoma) - Dormant Projects, H2 2016 52 List of Figures Number of Products under Development for Wilms' Tumor (Nephroblastoma), H2 2016 7 Number of Products under Development for Wilms' Tumor (Nephroblastoma) - Comparative Analysis, H2 2016 8 Number of Products under Development by Companies, H2 2016 9 Number of Products under Investigation by Universities/Institutes, H2 2016 10 Comparative Analysis by Clinical Stage Development, H2 2016 11 Assessment by Monotherapy Products, H2 2016 19 Number of Products by Top 10 Targets, H2 2016 20 Number of Products by Stage and Top 10 Targets, H2 2016 20 Number of Products by Top 10 Mechanism of Actions, H2 2016 22 Number of Products by Stage and Top 10 Mechanism of Actions, H2 2016 22 Number of Products by Routes of Administration, H2 2016 24 Number of Products by Stage and Routes of Administration, H2 2016 24 Number of Products by Molecule Types, H2 2016 26 Number of Products by Stage and Molecule Types, H2 2016 26

Exelixis Inc NanoSmart Pharmaceuticals Inc Recombio SL Selvita SA