PART 01: Executive summary • Highlights PART 02: Scope of the report • Market overview • Top-vendor offerings • Assumptions PART 03: Market research methodology • Research methodology • Economic indicators PART 04: Introduction • Key market highlights PART 05: Disease overview • Understanding the disease • Etiology • Signs and symptoms • Diagnosis • Management • Economic burden • Epidemiology PART 06: Pipeline portfolio PART 07: Market landscape • Market overview • Market size and forecast • Five forces analysis PART 08: Market segmentation by type of disease • RA • MS • PsA • IBD • AS • SLE • Global RA drugs market • Clinical trials for RA • Global MS drugs market • Global PsA drugs market • Global IBD drugs market • Global AS drugs market • Global SLE drugs market PART 09: Market segmentation by mechanism of action • TNF inhibitors • IL-1 blockers • COX inhibitors • PDE4 inhibitors • Others PART 10: Market segmentation by drug class • DMARDs • NSAIDs • Corticosteroids • Analgesics • Immunosuppressants • Others PART 11: Market segmentation by type of molecule • Biologics • Small molecules PART 12: Market segmentation by ROA • Oral • Parenteral • Topical PART 13: Market segmentation by dosage form • Solid • Liquid • Semi-solid PART 14: Geographical segmentation • Autoimmune diseases drugs market in the Americas • Autoimmune diseases drugs market in US • Autoimmune diseases drugs market in EMEA • Autoimmune diseases drugs market in APAC • Autoimmune diseases drugs market in Japan • Autoimmune diseases drugs market in China PART 15: Market drivers • Rising prevalence of autoimmune diseases • Growing older population • Dominance of biologics • Unmet medical needs • Promising pipeline PART 16: Impact of drivers PART 17: Market challenges • Increasing cost of biologics • Loss of patent exclusivity of branded therapies • Complex nature of autoimmune diseases • Preference for CAMs • Adverse effects PART 18: Impact of drivers and challenges PART 19: Market trends • Emergence of biosimilars • Patient assistance programs • Increase in public awareness programs • Strategic alliances • Popularity of off-label and traditional treatment options PART 20: Vendor landscape • Competitive scenario • Market analysis 2015 • AbbVie • Johnson & Johnson • Biogen • Amgen • Pfizer • F. Hoffmann-La Roche • Other prominent vendors PART 21: Appendix • List of abbreviations PART 22: Explore Technavio List of Exhibits Exhibit 01: Product offerings Exhibit 02: Etiology of autoimmune diseases Exhibit 03: Signs and symptoms of autoimmune diseases Exhibit 04: Diagnostic methods for autoimmune diseases Exhibit 05: Non-pharmacological therapies used for autoimmune diseases Exhibit 06: Pharmacotherapy therapies used for autoimmune diseases Exhibit 07: Top drugs for autoimmune diseases Exhibit 08: Average annual treatment costs of RA in US and Europe 2014 ($ billions) Exhibit 09: Average annual treatment costs of MS across countries 2014 ($ billions) Exhibit 10: Average annual treatment costs of PsA across countries 2014 ($ billions) Exhibit 11: Prevalence and incidence of SLE Exhibit 12: Pipeline molecules for RA Exhibit 13: Pipeline molecules for MS Exhibit 14: Pipeline molecules for PsA Exhibit 15: Pipeline molecules for CD Exhibit 16: Pipeline molecules for UC Exhibit 17: Pipeline molecules for SLE Exhibit 18: Global autoimmune diseases drugs market 2015-2020 ($ billions) Exhibit 19: Five forces analysis Exhibit 20: Global autoimmune diseases drugs market segmentation by type of disease Exhibit 21: Global autoimmune diseases drugs market by type of disease 2015 Exhibit 22: Global autoimmune diseases drugs market: YoY revenue and growth based on autoimmune diseases 2015-2020 Exhibit 23: Global RA drugs market 2015-2020 ($ billions) Exhibit 24: Global RA drugs market by drug class 2015 Exhibit 25: Top-vendor offerings for global RA drugs market Exhibit 26: RA clinical trial by Phase 2015 Exhibit 27: RA clinical trial by status 2015 Exhibit 28: Drivers and challenges of global RA drugs market Exhibit 29: Global MS drugs market 2015-2020 ($ billions) Exhibit 30: Global MS drugs market by molecule type 2015 Exhibit 31: Top-vendor offerings for global MS drugs market Exhibit 32: Drivers and challenges of global MS drugs market Exhibit 33: Global PsA drugs market 2015-2020 ($ billions) Exhibit 34: Global PsA drugs market segmentation by MOA 2015 Exhibit 35: Top-vendor offerings for global PsA drugs market Exhibit 36: Drivers and challenges of global PsA drugs market Exhibit 37: Global IBD drugs market 2015-2020 ($ billions) Exhibit 38: Global IBD drugs market by type of disease 2015 Exhibit 39: Global IBD drugs market by drug class 2015 Exhibit 40: Top-vendor offerings for global IBD drugs market Exhibit 41: Drivers and challenges of global IBD drugs market Exhibit 42: Global AS drugs market 2015-2020 ($ billions) Exhibit 43: Global AS drugs market by MOA 2015 Exhibit 44: Top-vendor offerings for global AS drugs market Exhibit 45: Drivers and challenges of global AS drugs market Exhibit 46: Global SLE drugs market 2015-2020 ($ billions) Exhibit 47: Drivers and challenges of global SLE drugs market Exhibit 48: Global autoimmune diseases drugs market segmentation by MOA Exhibit 49: Average percentage of patients receiving TNF inhibitors 2010 and 2015 Exhibit 50: Global autoimmune diseases drugs market share by MOA 2015 Exhibit 51: Global autoimmune diseases drugs market segmentation by drug class Exhibit 52: Examples of non-biologic DMARDs and biologic DMARDs for autoimmune diseases Exhibit 53: NSAIDs used to treat autoimmune diseases Exhibit 54: Global autoimmune diseases drugs market by drug class 2015 Exhibit 55: Global autoimmune diseases drugs market segmentation by type of molecule Exhibit 56: Global autoimmune diseases biologics market 2015-2020 ($ billions) Exhibit 57: Global autoimmune diseases small molecules market 2015-2020 ($ billions) Exhibit 58: Global autoimmune diseases drugs market by type of molecules 2015 Exhibit 59: Global autoimmune diseases drugs market segmentation by ROA Exhibit 60: Global autoimmune diseases drugs market segmentation by ROA 2015 Exhibit 61: Global autoimmune diseases drugs market segmentation by dosage form Exhibit 62: Global autoimmune disease drugs market segmentation by dosage form 2015 Exhibit 63: Global autoimmune diseases drugs market segmentation by geography 2015 Exhibit 64: Global autoimmune diseases drugs market revenue by geography 2015-2020 ($ billions) Exhibit 65: Autoimmune diseases drugs market in the Americas 2015-2020 ($ billions) Exhibit 66: Autoimmune diseases drugs market in America by country 2015 Exhibit 67: Autoimmune diseases drugs market in US 2015-2020 ($ billions) Exhibit 68: Drivers and challenges for autoimmune diseases drugs market in the US Exhibit 69: Autoimmune diseases drugs market in EMEA 2015-2020 ($ billions) Exhibit 70: Autoimmune diseases drugs market in APAC 2015-2020 ($ billions) Exhibit 71: Autoimmune diseases drugs market in Japan 2015-2020 ($ billions) Exhibit 72: Drivers and challenges for autoimmune diseases drugs market in Japan Exhibit 73: Autoimmune diseases drugs market in China 2015-2020 ($ billions) Exhibit 74: Global autoimmune diseases drugs market YoY revenue and growth based on geography 2015-2020 ($ billions) Exhibit 75: Population aged 60 years and over ($ millions) Exhibit 76: Biologics approval timeline by US FDA Exhibit 77: Some pipeline molecules under phases of development for autoimmune diseases Exhibit 78: Impact of drivers Exhibit 79: Average annual treatment cost of adalimumab, etanercept, and infliximab 2014 ($ millions) Exhibit 80: Approval and patent expiries of top selling biologics Exhibit 81: CAM therapies for autoimmune diseases Exhibit 82: Usage of CAM therapies among individuals in US 2014 Exhibit 83: Adverse effects associated with autoimmune disease therapies Exhibit 84: Impact of drivers and challenges Exhibit 85: Patient assistance programs for autoimmune diseases drugs Exhibit 86: Revenue share of major companies for autoimmune diseases 2015 Exhibit 87: YoY Sales comparison of top drugs 2013-2015 ($ billions) Exhibit 88: AbbVie: Product segmentation by revenue 20150 Exhibit 89: AbbVie: YoY growth rate and revenue of HUMIRA 2013-2015 ($ billions) Exhibit 90: AbbVie: YoY growth rate and revenue of HUMIRA in US 2013-2015 ($ billions) Exhibit 91: AbbVie: YoY growth rate and revenue of HUMIRA in ROW 2013-2015 ($ billions) Exhibit 92: Sales of HUMIRA in major markets Exhibit 93: AbbVie: Key takeaways Exhibit 94: Johnson & Johnson: Segmentation of key autoimmune diseases drugs 2014 Exhibit 95: Johnson & Johnson: YoY growth rate and revenue of Remicade 2013-2014 ($ billions) Exhibit 96: Johnson & Johnson: YoY growth rate and revenue of Remicade in US 2013-2015 ($ billions) Exhibit 97: Johnson & Johnson: YoY growth rate and revenue of Remicade in ROW 2013-2015 ($ billions) Exhibit 98: Johnson & Johnson: YoY growth rate and revenue of Stelara 2013-2015 ($ billions) Exhibit 99: Johnson & Johnson: YoY growth rate and revenue of Stelara in US 2013-2015 ($ billions) Exhibit 100: Johnson & Johnson: YoY growth rate and revenue of Stelara in ROW 2013-2015 ($ millions) Exhibit 101: Johnson & Johnson: YoY growth rate and revenue of Simponi/Simponi Aria 2013-2015 ($ billions) Exhibit 102: Johnson & Johnson: YoY growth rate and revenue of Simponi/Simponi Aria in US 2013-2015 ($ millions) Exhibit 103: Johnson & Johnson: YoY growth rate and revenue of Simponi/Simponi Aria in ROW 2013-2015 ($ millions) Exhibit 104: Johnson & Johnson: Key takeaways Exhibit 105: Biogen: Product segmentation of key autoimmune diseases drugs by revenue 2015 Exhibit 106: Top selling autoimmune diseases drugs Exhibit 107: Biogen: YoY growth rate and revenue of Tecfidera 2013-2015 ($ billions) Exhibit 108: Biogen: YoY growth rate and revenue of Avonex 2013-2015 ($ billions) Exhibit 109: Biogen: YoY growth rate and revenue of Tysabri 2013-2015 ($ billions) Exhibit 110: Biogen: YoY revenue of Plegridy 2014-2015 ($ millions) Exhibit 111: Biogen: YoY growth rate and revenue of Fampyra 2013-2015 ($ millions) Exhibit 112: Biogen: Key takeaways Exhibit 113: Amgen: YoY growth rate and revenue of Enbrel in US and Canada 2013-2015 ($ billions) Exhibit 114: Amgen: YoY growth rate and revenue of Enbrel in US 2013-2015 ($ billions) Exhibit 115: Amgen: YoY growth rate and revenue of Enbrel in Canada 2013-2015 ($ millions) Exhibit 116: Amgen: Key takeaways Exhibit 117: Pfizer: Autoimmune diseases drugs product segmentation by revenue 2014 Exhibit 118: Top selling autoimmune diseases drugs Exhibit 119: Pfizer: YoY growth rate and revenue of Enbrel (outside US and Canada) 2013-2015 ($ billions) Exhibit 120: Pfizer: YoY growth rate and revenue of Celebrex 2013-2015 ($ billions) Exhibit 121: Pfizer: YoY growth rate and revenue of Xeljanz 2012-2014 ($ millions) Exhibit 122: Pfizer: Key takeaways Exhibit 123: Top selling autoimmune diseases drugs Exhibit 124: F. Hoffmann-La Roche: YoY growth rate and revenue of Actemra/RoActemra 2013-2015 ($ billions) Exhibit 125: F. Hoffmann-La Roche: Actemra/RoActemra geographic segmentation by revenue 20155 Exhibit 126: F. Hoffmann-La Roche: YoY growth rate and revenue of MabThera/Rituxan (oncology and immunology indications) 2013-2015 ($ billions) Exhibit 127: F. Hoffmann-La Roche: YoY growth rate and revenue of MabThera/Rituxan (immunology indications only) 2013-2015 ($ billions) Exhibit 128: F. Hoffmann-La Roche: Geographic segmentation of MabThera/Rituxan by revenue 2015 Exhibit 129: F. Hoffmann-La Roche: Key takeaways

AbbVie Inc., Amgen Inc., Biogen, F. Hoffmann-La Roche, Johnson & Johnson Private Limited, Pfizer Inc, Ablynx, AB Science, Acorda Therapeutics, Alder BioPharmaceuticals, Antares Pharma, Astellas Pharma, AstraZeneca, Baxter, Boehringer Ingelheim, Can-Fite BioPharma, Celgene, Celltrion, ChemoCentryx, Coherus BioSciences, Daiichi Sankyo, Eisai, Eli Lilly, Gilead Sciences, GSK, Hospira, Idera Pharmaceuticals, Immunomedics, ImmuPharma, Incyte, Invion, KaloBios Pharmaceuticals, Lexicon Pharmaceuticals, Merck, MedImmune, Morphotek, Novo Nordisk, Novartis, Opexa Therapeutics, Principia Biopharma, Regeneron Pharmaceuticals, Sandoz, Sanofi, Santarus, Takeda Pharmaceuticals, UCB, Vaccinex, Vertex Pharmaceuticals, Vitae Pharmaceuticals.