Table of Contents Table of Contents 2 List of Tables 3 List of Figures 4 Report Guidance 5 Clinical Trials by Region 6 Clinical Trials and Average Enrollment by Country 7 Top Five Countries Contributing to Clinical Trials in Asia-Pacific 9 Top Five Countries Contributing to Clinical Trials in Europe 10 Top Countries Contributing to Clinical Trials in North America 11 Top Countries Contributing to Clinical Trials in Middle East and Africa 12 Clinical Trials by G7 Countries: Proportion of High-Grade Glioma to Oncology Clinical Trials 13 Clinical Trials by Phase in G7 Countries 14 Clinical Trials in G7 Countries by Trial Status 15 Clinical Trials by E7 Countries: Proportion of High-Grade Glioma to Oncology Clinical Trials 16 Clinical Trials by Phase in E7 Countries 17 Clinical Trials in E7 Countries by Trial Status 18 Clinical Trials by Phase 19 In Progress Trials by Phase 20 Clinical Trials by Trial Status 21 Clinical Trials by End Point Status 22 Subjects Recruited Over a Period of Time 23 Clinical Trials by Sponsor Type 24 Prominent Sponsors 25 Top Companies Participating in High-Grade Glioma Therapeutics Clinical Trials 26 Prominent Drugs 27 Latest Clinical Trials News on High-Grade Glioma 28 May 13, 2016: Tocagen to Present Clinical and Preclinical Data at Three Scientific Meetings 28 May 03, 2016: Tocagen Presents Intravenous Toca 511 Clinical Data at the 84th AANS Annual Scientific Meeting 28 Apr 13, 2016: Tocagen to Present Data from Clinical Trials and Preclinical Programs at Four Scientific Conferences 29 Clinical Trial Profile Snapshots 30 Appendix 194 Abbreviations 194 Definitions 194 Research Methodology 195 Secondary Research 195 About GlobalData 196 Contact Us 196 Disclaimer 196 Source 197

List of Tables High-Grade Glioma Therapeutics, Global, Clinical Trials by Region, 2016* 6 High-Grade Glioma Therapeutics, Global, Clinical Trials and Average Enrollment by Top Countries, 2016* 7 High-Grade Glioma Therapeutics, Global, Clinical Trials In Progress by Top Countries, 2016* 8 High-Grade Glioma Therapeutics Clinical Trials, Asia-Pacific, Top Five Countries, 2016* 9 High-Grade Glioma Therapeutics Clinical Trials, Europe, Top Five Countries, 2016* 10 High-Grade Glioma Therapeutics Clinical Trials, North America, Top Countries, 2016* 11 High-Grade Glioma Therapeutics Clinical Trials, Middle East and Africa, Top Countries, 2016* 12 Proportion of High-Grade Glioma to Oncology Clinical Trials, G7 Countries (%), 2016* 13 High-Grade Glioma Therapeutics, G7 Countries, Clinical Trials by Phase, 2016* 14 High-Grade Glioma Therapeutics, G7 Countries, Clinical Trials by Trial Status, 2016* 15 Proportion of High-Grade Glioma to Oncology Clinical Trials, E7 Countries (%), 2016* 16 High-Grade Glioma Therapeutics, E7 Countries, Clinical Trials by Phase, 2016* 17 High-Grade Glioma Therapeutics, E7 Countries, Clinical Trials by Trial Status, 2016* 18 High-Grade Glioma Therapeutics, Global, Clinical Trials by Phase, 2016* 19 High-Grade Glioma Therapeutics, Global, Clinical Trials In Progress by Phase 2016* 20 High-Grade Glioma Therapeutics, Global, Clinical Trials by Trial Status, 2016* 21 High-Grade Glioma Therapeutics Clinical Trials, Global, by End Point Status, 2016* 22 High-Grade Glioma Therapeutics Clinical Trials, Global, Average Enrollment Target Trends, 2011-2015 23 High-Grade Glioma Therapeutics Market, Global, Clinical Trials by Sponsor Type, 2016* 24 High-Grade Glioma Therapeutics Clinical Trials, Global, Key Sponsors, 2016* 25 High-Grade Glioma Therapeutics Clinical Trials, Global, Top Companies by Phase, 2016* 26 High-Grade Glioma Therapeutics Clinical Trials, Global, Ongoing Clinical Trials by Prominent Drugs, 2016* 27 List of Figures High-Grade Glioma Therapeutics, Global, Clinical Trials by Region (%), 2016* 6 High-Grade Glioma Therapeutics, Global, Clinical Trials and Average Enrollment by Top Countries, 2016* 7 High-Grade Glioma Therapeutics, Global, Clinical Trials In Progress by Top Countries, 2016* 8 High-Grade Glioma Therapeutics Clinical Trials, Asia-Pacific, Top Five Countries (%), 2016* 9 High-Grade Glioma Therapeutics Clinical Trials, Europe, Top Five Countries (%), 2016* 10 High-Grade Glioma Therapeutics Clinical Trials, North America, Top Countries (%), 2016* 11 High-Grade Glioma Therapeutics Clinical Trials, Middle East and Africa, Top Countries (%), 2016* 12 Proportion of High-Grade Glioma to Oncology Clinical Trials, G7 Countries (%), 2016* 13 High-Grade Glioma Therapeutics, G7 Countries, Clinical Trials by Phase, 2016* 14 High-Grade Glioma Therapeutics, G7 Countries, Clinical Trials by Trial Status, 2016* 15 Proportion of High-Grade Glioma to Oncology Clinical Trials, E7 Countries (%), 2016* 16 High-Grade Glioma Therapeutics, E7 Countries, Clinical Trials by Phase, 2016* 17 High-Grade Glioma Therapeutics, E7 Countries, Clinical Trials by Trial Status, 2016* 18 High-Grade Glioma Therapeutics, Global, Clinical Trials by Phase (%), 2016* 19 High-Grade Glioma Therapeutics, Global, Clinical Trials In Progress by Phase, 2016* 20 High-Grade Glioma Therapeutics, Global, Clinical Trials by Trial Status, 2016* 21 High-Grade Glioma Therapeutics Clinical Trials, Global, by End Point Status, 2016* 22 High-Grade Glioma Therapeutics Clinical Trials, Global, Average Enrollment Target Trends, 2011-2015 23 High-Grade Glioma Therapeutics Market, Global, Clinical Trials by Sponsor Type (%), 2016* 24 High-Grade Glioma Therapeutics Clinical Trials, Global, Key Sponsors, 2016* 25 High-Grade Glioma Therapeutics Clinical Trials, Global, Top Companies by Phase, 2016* 26 High-Grade Glioma Therapeutics Clinical Trials, Global, Ongoing Clinical Trials by Prominent Drugs, 2016* 27 GlobalData Methodology 195

F. Hoffmann-La Roche Ltd. Novartis AG Tocagen Inc. Sanofi Pfizer Inc. Merck & Co., Inc. Eli Lilly and Company Eisai Co., Ltd. C. H. Boehringer Sohn AG & Co. KG Bayer AG