1 Table of Contents 1 Table of Contents 6 1.1 List of Tables 9 1.2 List of Figures 11 2 Introduction 13 2.1 Catalyst 13 2.2 Related Reports 14 3 Market Access 15 3.1 Reimbursement Trends 15 3.1.1 North America 15 3.1.2 Europe 19 3.1.3 Asia-Pacific 21 3.1.4 South America 23 3.2 Mergers and Acquisitions/Key Partnerships 24 4 Unmet Needs and Market Opportunity Analysis 26 4.1 High Quality Data for Drug-eluting Balloons in Specific Indications 26 4.2 Minimizing Periprocedural Stroke Risk During Carotid Artery Interventions 27 4.2.1 Anti-thrombotic Coatings 27 4.2.2 Occlusion with Flow Reversal 27 4.2.3 Integrated Embolic Protection 28 4.3 Motorized Delivery Systems 29 4.4 Reducing Reintervention Rates 30 4.4.1 Controlled Drug Delivery Mechanisms 31 4.4.2 Improving Physician Training in Endovascular Techniques 31 5 Competitive Assessment 33 5.1 Market Share Analysis 33 5.1.1 North America 33 5.1.2 Europe 38 5.1.3 Asia-Pacific 41 5.1.4 South America 46 5.2 Key Companies and Product Profiles 50 5.2.1 Abbott Vascular 50 5.2.2 Biotronik 54 5.2.3 Boston Scientific 59 5.2.4 C.R. Bard 63 5.2.5 Cook Medical 66 5.2.6 Cordis (Cardinal Health) 70 5.2.7 Medtronic 72 5.2.8 Terumo 76 5.2.9 W.L. Gore 79 5.2.10 Other Players 82 5.3 Pipeline Products Assessment 89 6 Market Outlook 92 6.1 Procedure Trends 92 6.1.1 Treatment Paradigm 92 6.1.2 Lower Extremity Revascularization 93 6.1.3 Carotid Artery Stenting 99 6.1.4 Renal Artery Stenting 100 6.2 Global Market Drivers and Barriers 101 6.2.1 Driver: Rising Disease Prevalence 101 6.2.2 Driver: Rising Endovascular Procedure Rates 102 6.2.3 Driver: Improved Solutions for Superficial Femoral Artery Revascularization 102 6.2.4 Driver: Development of Low-profile Delivery Systems 103 6.2.5 Driver: Reduced Stent Fracture Rates with Second Generation Stents 104 6.2.6 Barrier: Impact of Current Reimbursement Schemes 104 6.2.7 Barrier: Lack of Rigorous Clinical Trials for Peripheral Bioabsorbable Stents 106 6.3 Market Outlooks by Segment 107 6.3.1 Global Overview 107 6.3.2 Lower Extremity Stents 109 6.3.3 Percutaneous Transluminal Angioplasty Balloons 112 6.3.4 Carotid Stents 114 6.3.5 Renal Stents 115 6.4 Market Outlooks by Geography 116 6.4.1 Global Overview 116 6.4.2 North America 119 6.4.3 Europe 123 6.4.4 Asia-Pacific 126 6.4.5 South America 129 7 Appendix 132 7.1 Bibliography 132 7.2 Abbreviations 146 7.3 Methodology 150 7.3.1 Overview 150 7.3.2 Coverage 150 7.3.3 Secondary Research 150 7.4 Forecasting Methodology 151 7.5 Physicians and Specialists Included in This Study 152 7.5.1 Key Opinion Leaders 152 7.6 Primary Research Summary 154 7.7 About the Authors 155 7.7.1 Analysts 155 7.7.2 Global Head of Medical Devices 155 7.7.3 About GlobalData 155 7.8 Disclaimer 156

1.1 List of Tables Table 1: Medicare National Average of Inpatient Hospital Reimbursement for Peripheral Vascular Interventions, 2015-2016 17 Table 2: Hospital Outpatient Reimbursement for Peripheral Vascular Interventions, 2015 17 Table 3: Key Mergers, Acquisitions, and Partnerships in Peripheral Vascular Interventions Market 24 Table 4: Abbott Vascular - Company SWOT Analysis 50 Table 5: Abbott Vascular - Marketed Products Assessment 51 Table 6: Abbott Vascular - Clinical Trials to Watch 54 Table 7: Biotronik - Company SWOT Analysis 55 Table 8: Biotronik - Marketed Products Assessment 56 Table 9: Biotronik - Clinical Trials to Watch 58 Table 10: Boston Scientific - Company SWOT Analysis 59 Table 11: Boston Scientific - Marketed Products Assessment 60 Table 12: Boston Scientific - Clinical Trials to Watch 62 Table 13: C.R. Bard - Company SWOT Analysis 63 Table 14: C.R. Bard - Marketed Products Assessment 64 Table 15: C.R. Bard - Clinical Trials to Watch 66 Table 16: Cook Medical - Company SWOT Analysis 67 Table 17: Cook Medical - Marketed Products Assessment 68 Table 18: Cook Medical - Clinical Trials to Watch 70 Table 19: Cordis (Cardinal Health) - Company SWOT Analysis 70 Table 20: Cordis (Cardinal Health) - Marketed Products Assessment 71 Table 21: Cordis (Cardinal Health) - Clinical Trials to Watch 72 Table 22: Medtronic - Company SWOT Analysis 73 Table 23: Medtronic - Marketed Products Assessment 74 Table 24: Medtronic - Clinical Trials to Watch 76 Table 25: Terumo - Company SWOT Analysis 77 Table 26: Terumo - Marketed Products Assessment 78 Table 27: Terumo - Clinical Trials to Watch 79 Table 28: W.L. Gore - Company SWOT Analysis 80 Table 29: W.L. Gore - Marketed Products Assessment 80 Table 30: W.L. Gore - Clinical Trials to Watch 82 Table 31: Other Players Assessment 83 Table 32: Other Clinical Trials to Watch 87 Table 33: Pipeline Products Assessment 89 Table 34: Global Peripheral Vascular Interventions Market Forecast ($m), by Segment, 2012-2022 107 Table 35: Global Lower Extremity Stents Market Forecast ($m), 2012-2022 109 Table 36: Global PTA Balloons Market Forecast ($m), 2012-2022 112 Table 37: Global Carotid Stents Market Forecast ($m), 2012-2022 114 Table 38: Global Renal Stents Market Forecast ($m), 2012-2022 115 Table 39: Global Peripheral Vascular Interventions Market Forecast ($m), by Country, 2012-2022 117 Table 40: North America Peripheral Vascular Interventions Market Forecast ($m), by Segment, 2012-2022 120 Table 41: Europe Peripheral Vascular Interventions Market Forecast ($m), by Segment, 2012-2022 123 Table 42: Asia-Pacific Peripheral Vascular Interventions Market Forecast ($m), by Segment, 2012-2022 126 Table 43: South America Peripheral Vascular Interventions Market Forecast ($m), by Segment, 2012-2022 129 1.2 List of Figures Figure 1: North America Market Shares for Lower Extremity Stents, by Company, 2015 33 Figure 2: North America Market Shares for Standard PTA Balloons, by Company, 2015 35 Figure 3: North America Market Shares for PTA DEB, by Company, 2015 36 Figure 4: North America Market Shares for Carotid Stents, by Company, 2015 37 Figure 5: Europe Market Shares for Lower Extremity Stents, by Company, 2015 38 Figure 6: Europe Market Shares for Standard PTA Balloons, by Company, 2015 39 Figure 7: Europe Market Shares for PTA DEB, by Company, 2015 40 Figure 8: Europe Market Shares for Carotid Stents, by Company, 2015 41 Figure 9: APAC Market Shares for Lower Extremity Stents, by Company, 2015 42 Figure 10: APAC Market Shares for Standard PTA Balloons, by Company, 2015 43 Figure 11: APAC Market Shares for Standard PTA DEB, by Company, 2015 44 Figure 12: APAC Market Shares for Carotid Stents, by Company, 2015 45 Figure 13: South America Market Shares for Lower Extremity Stents, by Company, 2015 46 Figure 14: South America Market Shares for PTA Balloons, by Company, 2015 47 Figure 15: South America Market Shares for PTA DEB, by Company, 2015 48 Figure 16: South America Market Shares for Carotid Stents, by Company, 2015 49 Figure 17: Treatment Modalities - PAD 92 Figure 18: Global Procedure Volume Forecast for Stenting in the Lower Extremity, by Artery, 2012-2022 93 Figure 19: Global Procedure Volume Forecast for Standard Balloon Angioplasty in the Lower Extremity, by Artery, 2012-2022 94 Figure 20: Global Procedure Volume Forecast for DEB Angioplasty in the Lower Extremity, by Artery, 2012-2022 95 Figure 21: Endovascular Treatment Patterns in the Iliac Arteries, by Region, 2015 96 Figure 22: Endovascular Treatment Patterns in the Femoropopliteal Arteries, by Region, 2015 98 Figure 23: Endovascular Treatment Patterns in the Infrapopliteal Arteries, by Region, 2015 99 Figure 24: Global Procedure Volume Forecast for Carotid Artery Stenting, 2012-2022 100 Figure 25: Global Procedure Volume Forecast for Renal Artery Stenting, 2012-2022 101 Figure 26: Global Peripheral Vascular Interventions Market Forecast ($m), by Segment, 2012-2022 107 Figure 27: Global Peripheral Vascular Interventions Market Comparison, by Segment, 2015 and 2022 108 Figure 28: Global Lower Extremity Stents Market Forecast ($m), 2012-2022 109 Figure 29: Lower Extremity Stents Market Comparison, by Segment, 2015 and 2022 111 Figure 30: Global PTA Balloons Market Forecast ($m), 2012-2022 112 Figure 31: Global Carotid Stents Market Forecast ($m), 2012-2022 114 Figure 32: Global Renal Stents Market Forecast ($m), 2012-2022 115 Figure 33: Global Peripheral Vascular Interventions Market Forecast ($m), by Country, 2012-2022 116 Figure 34: Global Peripheral Vascular Interventions Market Comparison, by Country, 2015 and 2022 118 Figure 35: North America Peripheral Vascular Interventions Market Forecast ($m), by Segment, 2012-2022 119 Figure 36: North America Peripheral Vascular Interventions Market Comparison, by Segment, 2015 and 2022 122 Figure 37: Europe Peripheral Vascular Interventions Market Forecast ($m), by Segment, 2012-2022 123 Figure 38: Europe Peripheral Vascular Interventions Market Comparison, by Segment, 2015 and 2022 125 Figure 39: APAC Peripheral Vascular Interventions Market Forecast ($m), by Segment, 2012-2022 126 Figure 40: APAC Peripheral Vascular Interventions Market Comparison, by Segment, 2015 and 2022 128 Figure 41: South America Peripheral Vascular Interventions Market Forecast ($m), by Segment, 2012-2022 129 Figure 42: South America Peripheral Vascular Interventions Market Comparison, by Segment, 2015 and 2022 131 Figure 43: Peripheral Vascular Survey Primary Research Participants, by Country 154

Abbott Vascular Biotronik Boston Scientific C.R. Bard Cook Medical Cordis (Cardinal Health) Medtronic Terumo W.L. Gore