1 Table of Contents 1 Table of Contents 2 1.1 List of Tables 3 1.2 List of Figures 4 2 Introduction 5 2.1 Thoracic Aortic Stent Grafts Overview 5 3 Products under Development 6 3.1 Thoracic Aortic Stent Grafts - Pipeline Products by Stage of Development 6 3.2 Thoracic Aortic Stent Grafts - Pipeline Products by Territory 7 3.3 Thoracic Aortic Stent Grafts - Pipeline Products by Regulatory Path 8 3.4 Thoracic Aortic Stent Grafts - Pipeline Products by Estimated Approval Date 9 3.5 Thoracic Aortic Stent Grafts - Ongoing Clinical Trials 10 4 Thoracic Aortic Stent Grafts - Pipeline Products under Development by Companies 11 4.1 Thoracic Aortic Stent Grafts Companies - Pipeline Products by Stage of Development 11 4.2 Thoracic Aortic Stent Grafts - Pipeline Products by Stage of Development 12 5 Thoracic Aortic Stent Grafts Companies and Product Overview 13 5.1 Cook Medical Incorporated Company Overview 13 5.1.1 Cook Medical Incorporated Pipeline Products & Ongoing Clinical Trials Overview 13 5.2 Evasc Medical Systems Corp. Company Overview 17 5.2.1 Evasc Medical Systems Corp. Pipeline Products & Ongoing Clinical Trials Overview 17 5.3 Medtronic plc Company Overview 19 5.3.1 Medtronic plc Pipeline Products & Ongoing Clinical Trials Overview 19 5.4 MicroPort Scientific Corporation Company Overview 25 5.4.1 MicroPort Scientific Corporation Pipeline Products & Ongoing Clinical Trials Overview 25 5.5 St. Jude Medical, Inc. Company Overview 30 5.5.1 St. Jude Medical, Inc. Pipeline Products & Ongoing Clinical Trials Overview 30 5.6 TriVascular, Inc. Company Overview 32 5.6.1 TriVascular, Inc. Pipeline Products & Ongoing Clinical Trials Overview 32 5.7 W. L. Gore & Associates, Inc. Company Overview 34 5.7.1 W. L. Gore & Associates, Inc. Pipeline Products & Ongoing Clinical Trials Overview 34 6 Thoracic Aortic Stent Grafts- Recent Developments 38 6.1 Apr 28, 2016: Merit Medical Reports Sales Up 6.6% for the Quarter Ended March 31, 2016 38 6.2 Feb 22, 2016: Merit Medical Reports Results for Fourth Quarter and Year Ended December 31, 2015 38 6.3 Jan 26, 2016: First U.S. patient treated following FDA approval of Cook Medical’s Zenith Alpha Thoracic Endovascular Graft 40 6.4 Nov 06, 2015: Merit Medical Names New Chief Financial Officer 40 6.5 Nov 02, 2015: Medtronic Unveils New Aortic and Peripheral Data from Two Late-Breaking Clinical Trials at VIVA 2015 41 6.6 Oct 22, 2015: Merit Medical Announces Results for the Quarter Ended September 30, 2015 42 6.7 Sep 17, 2015: Cook Medical receives FDA approval for the Zenith Alpha Thoracic Endovascular Graft 44 6.8 Jul 23, 2015: Merit Medical Reports Record Revenues for the Quarter and Six Months Ended June 30, 2015 44 7 Appendix 47 7.1 Methodology 47 7.2 About GlobalData 49 7.3 Contact Us 50 7.4 Disclaimer 50

1.1 List of Tables Table 1: Thoracic Aortic Stent Grafts - Pipeline Products by Stage of Development 6 Table 2: Thoracic Aortic Stent Grafts - Pipeline Products by Territory 7 Table 3: Thoracic Aortic Stent Grafts - Pipeline Products by Regulatory Path 8 Table 4: Thoracic Aortic Stent Grafts - Pipeline Products by Estimated Approval Date 9 Table 5: Thoracic Aortic Stent Grafts - Ongoing Clinical Trials 10 Table 6: Thoracic Aortic Stent Grafts Companies - Pipeline Products by Stage of Development 11 Table 7: Thoracic Aortic Stent Grafts - Pipeline Products by Stage of Development 12 Table 8: Cook Medical Incorporated Pipeline Products & Ongoing Clinical Trials Overview 13 Table 9: Zenith TX2 LP TAA Endovascular Graft - Product Status 14 Table 10: Zenith TX2 LP TAA Endovascular Graft - Product Description 14 Table 11: Cook Medical Incorporated - Ongoing Clinical Trials Overview 15 Table 12: Zenith TX2 LP TAA Endovascular Graft - Zenith TX2 Low Profile Endovascular Graft for Blunt Thoracic Aortic Injury (TRANSFIX) 16 Table 13: Zenith TX2 LP TAA Endovascular Graft - Zenith TX2 Low Profile TAA Endovascular Graft Clinical Study 16 Table 14: Zenith TX2 LP TAA Endovascular Graft - Zenith TX2 Low Profile TAA Endovascular Graft Clinical Study 16 Table 15: Evasc Medical Systems Corp. Pipeline Products & Ongoing Clinical Trials Overview 17 Table 16: TAS System - Product Status 18 Table 17: TAS System - Product Description 18 Table 18: Medtronic plc Pipeline Products & Ongoing Clinical Trials Overview 19 Table 19: Valiant EVO - Product Status 20 Table 20: Valiant EVO - Product Description 20 Table 21: Valiant Mona LSA System - Product Status 21 Table 22: Valiant Mona LSA System - Product Description 21 Table 23: Medtronic plc - Ongoing Clinical Trials Overview 22 Table 24: Valiant Mona LSA System - Valiant Mona LSA Stent Graft System Early Feasibility Study 23 Table 25: Valiant Mona LSA System - Valiant Mona LSA Thoracic Stent Graft System Feasibility Study 23 Table 26: Valiant EVO - Valiant Evo International Clinical Trial 24 Table 27: Valiant EVO - Valiant Evo US Clinical Trial 24 Table 28: MicroPort Scientific Corporation Pipeline Products & Ongoing Clinical Trials Overview 25 Table 29: Castor Branched Stent Graft System - Product Status 26 Table 30: Castor Branched Stent Graft System - Product Description 26 Table 31: Hercules - LP - Product Status 27 Table 32: Hercules - LP - Product Description 27 Table 33: MicroPort Scientific Corporation - Ongoing Clinical Trials Overview 28 Table 34: Castor Branched Stent Graft System - A Multi-center Trial of Castor Single-Branched Stent Graft System for Endovascular Repair of Aortic Dissection 29 Table 35: St. Jude Medical, Inc. Pipeline Products & Ongoing Clinical Trials Overview 30 Table 36: Amplatzer TAA Vascular Graft - Product Status 31 Table 37: Amplatzer TAA Vascular Graft - Product Description 31 Table 38: TriVascular, Inc. Pipeline Products & Ongoing Clinical Trials Overview 32 Table 39: Ovation Thoracic Stent Graft System - Product Status 33 Table 40: Ovation Thoracic Stent Graft System - Product Description 33 Table 41: W. L. Gore & Associates, Inc. Pipeline Products & Ongoing Clinical Trials Overview 34 Table 42: GORE TAG Thoracic Branch Endoprosthesis - Product Status 35 Table 43: GORE TAG Thoracic Branch Endoprosthesis - Product Description 35 Table 44: W. L. Gore & Associates, Inc. - Ongoing Clinical Trials Overview 36 Table 45: GORE TAG Thoracic Branch Endoprosthesis - GORE TAG Thoracic Branch Endoprosthesis Early Feasibility Study 37 Table 46: Glossary 48 1.2 List of Figures Figure 1: Thoracic Aortic Stent Grafts - Pipeline Products by Stage of Development 6 Figure 2: Thoracic Aortic Stent Grafts - Pipeline Products by Territory 7 Figure 3: Thoracic Aortic Stent Grafts - Pipeline Products by Regulatory Path 8 Figure 4: Thoracic Aortic Stent Grafts - Pipeline Products by Estimated Approval Date 9 Figure 5: Thoracic Aortic Stent Grafts - Ongoing Clinical Trials 10

Cook Medical Incorporated Evasc Medical Systems Corp. Medtronic plc MicroPort Scientific Corporation St. Jude Medical, Inc. TriVascular, Inc. W. L. Gore & Associates, Inc.