1 Table of Contents 1 Table of Contents 2 1.1 List of Tables 4 1.2 List of Figures 5 2 Introduction 6 2.1 Optical Coherence Tomography (OCT) Overview 6 3 Products under Development 7 3.1 Optical Coherence Tomography (OCT) - Pipeline Products by Stage of Development 7 3.2 Optical Coherence Tomography (OCT) - Pipeline Products by Territory 8 3.3 Optical Coherence Tomography (OCT) - Pipeline Products by Regulatory Path 9 3.4 Optical Coherence Tomography (OCT) - Pipeline Products by Estimated Approval Date 10 3.5 Optical Coherence Tomography (OCT) - Ongoing Clinical Trials 11 4 Optical Coherence Tomography (OCT) - Pipeline Products under Development by Companies 12 4.1 Optical Coherence Tomography (OCT) Companies - Pipeline Products by Stage of Development 12 4.2 Optical Coherence Tomography (OCT) - Pipeline Products by Stage of Development 13 5 Optical Coherence Tomography (OCT) Companies and Product Overview 14 5.1 Canon U.S.A., Inc. Company Overview 14 5.1.1 Canon U.S.A., Inc. Pipeline Products & Ongoing Clinical Trials Overview 14 5.2 Cleveland Clinic Hospital Company Overview 16 5.2.1 Cleveland Clinic Hospital Pipeline Products & Ongoing Clinical Trials Overview 16 5.3 Compact Imaging Inc. Company Overview 17 5.3.1 Compact Imaging Inc. Pipeline Products & Ongoing Clinical Trials Overview 17 5.4 Duke University Company Overview 18 5.4.1 Duke University Pipeline Products & Ongoing Clinical Trials Overview 18 5.5 George Washington University Company Overview 23 5.5.1 George Washington University Pipeline Products & Ongoing Clinical Trials Overview 23 5.6 Heidelberg Engineering GmbH Company Overview 25 5.6.1 Heidelberg Engineering GmbH Pipeline Products & Ongoing Clinical Trials Overview 25 5.7 Leica Microsystems GmbH Company Overview 28 5.7.1 Leica Microsystems GmbH Pipeline Products & Ongoing Clinical Trials Overview 28 5.8 OptoQuest Company Overview 32 5.8.1 OptoQuest Pipeline Products & Ongoing Clinical Trials Overview 32 5.9 Optos Plc Company Overview 33 5.9.1 Optos Plc Pipeline Products & Ongoing Clinical Trials Overview 33 5.10 Sinoora Inc. Company Overview 37 5.10.1 Sinoora Inc. Pipeline Products & Ongoing Clinical Trials Overview 37 5.11 University of California, Berkeley Company Overview 38 5.11.1 University of California, Berkeley Pipeline Products & Ongoing Clinical Trials Overview 38 5.12 University of Rochester Company Overview 40 5.12.1 University of Rochester Pipeline Products & Ongoing Clinical Trials Overview 40 5.13 Volcano Corporation Company Overview 41 5.13.1 Volcano Corporation Pipeline Products & Ongoing Clinical Trials Overview 41 6 Optical Coherence Tomography (OCT)- Recent Developments 43 6.1 Feb 12, 2016: Optovue’s AngioVue Imaging System Receives FDA Clearance 43 6.2 Dec 14, 2015: Leica receives FDA approval for EnFocus OCT 43 6.3 Nov 19, 2015: Entellus Medical Enters into Co-Marketing Agreement with Xoran Technologies 44 6.4 Nov 13, 2015: Optovue Showcases Total Cornea Power for Better Eyesight After Cataract Surgery at AAO 2015 44 6.5 Sep 01, 2015: Leica Microsystems now offers Optical Coherence Tomography imaging system for clinical ophthalmology 45 6.6 Aug 25, 2015: Heidelberg Engineering Enters into Licensing Agreement with Massachusetts General Hospital 45 6.7 Jun 10, 2015: Optovue Introduces AngioVue OCTA in Glaucoma 45 6.8 Jun 01, 2015: Leica Microsystems to Acquire Bioptigen 46 7 Appendix 47 7.1 Methodology 47 7.2 About GlobalData 49 7.3 Contact Us 50 7.4 Disclaimer 50

1.1 List of Tables Table 1: Optical Coherence Tomography (OCT) - Pipeline Products by Stage of Development 7 Table 2: Optical Coherence Tomography (OCT) - Pipeline Products by Territory 8 Table 3: Optical Coherence Tomography (OCT) - Pipeline Products by Regulatory Path 9 Table 4: Optical Coherence Tomography (OCT) - Pipeline Products by Estimated Approval Date 10 Table 5: Optical Coherence Tomography (OCT) - Ongoing Clinical Trials 11 Table 6: Optical Coherence Tomography (OCT) Companies - Pipeline Products by Stage of Development 12 Table 7: Optical Coherence Tomography (OCT) - Pipeline Products by Stage of Development 13 Table 8: Canon U.S.A., Inc. Pipeline Products & Ongoing Clinical Trials Overview 14 Table 9: SPOCT HR - Product Status 15 Table 10: SPOCT HR - Product Description 15 Table 11: Cleveland Clinic Hospital Pipeline Products & Ongoing Clinical Trials Overview 16 Table 12: Interoperative OCT System - Product Status 16 Table 13: Interoperative OCT System - Product Description 16 Table 14: Compact Imaging Inc. Pipeline Products & Ongoing Clinical Trials Overview 17 Table 15: MRO Optical Imaging Sensor - Product Status 17 Table 16: MRO Optical Imaging Sensor - Product Description 17 Table 17: Duke University Pipeline Products & Ongoing Clinical Trials Overview 18 Table 18: HH - SDOCT - Product Status 19 Table 19: HH - SDOCT - Product Description 19 Table 20: Microscope Integrated OCT System - Product Status 20 Table 21: Microscope Integrated OCT System - Product Description 20 Table 22: Duke University - Ongoing Clinical Trials Overview 21 Table 23: Microscope Integrated OCT System - Intraoperative OCT Guidance of Intraocular Surgery 22 Table 24: George Washington University Pipeline Products & Ongoing Clinical Trials Overview 23 Table 25: Amplified Bimorph Scanning Mirror System - Product Status 24 Table 26: Amplified Bimorph Scanning Mirror System - Product Description 24 Table 27: Heidelberg Engineering GmbH Pipeline Products & Ongoing Clinical Trials Overview 25 Table 28: Cataract And Refractive Imaging Platform - Product Status 26 Table 29: Cataract And Refractive Imaging Platform - Product Description 26 Table 30: SPECTRALIS OCT2 Module - OCT Angiography - Product Status 27 Table 31: SPECTRALIS OCT2 Module - OCT Angiography - Product Description 27 Table 32: Leica Microsystems GmbH Pipeline Products & Ongoing Clinical Trials Overview 28 Table 33: DI-SDOCT Imaging System - Product Status 29 Table 34: DI-SDOCT Imaging System - Product Description 29 Table 35: Microscope Integrated Intraoperative OCT - Product Status 30 Table 36: Microscope Integrated Intraoperative OCT - Product Description 30 Table 37: SDOCT Scanner - Product Status 31 Table 38: SDOCT Scanner - Product Description 31 Table 39: OptoQuest Pipeline Products & Ongoing Clinical Trials Overview 32 Table 40: Vectralis - Product Status 32 Table 41: Vectralis - Product Description 32 Table 42: Optos Plc Pipeline Products & Ongoing Clinical Trials Overview 33 Table 43: Falcon I - Product Status 34 Table 44: Falcon I - Product Description 34 Table 45: Falcon II - Product Status 35 Table 46: Falcon II - Product Description 35 Table 47: Lotte - Product Status 36 Table 48: Lotte - Product Description 36 Table 49: Sinoora Inc. Pipeline Products & Ongoing Clinical Trials Overview 37 Table 50: On-chip Spectral Coherence Tomography System - Product Status 37 Table 51: On-chip Spectral Coherence Tomography System - Product Description 37 Table 52: University of California, Berkeley Pipeline Products & Ongoing Clinical Trials Overview 38 Table 53: Directional Optical Coherence Tomography Device - Product Status 39 Table 54: Directional Optical Coherence Tomography Device - Product Description 39 Table 55: University of Rochester Pipeline Products & Ongoing Clinical Trials Overview 40 Table 56: Scanning Optical System - Product Status 40 Table 57: Scanning Optical System - Product Description 40 Table 58: Volcano Corporation Pipeline Products & Ongoing Clinical Trials Overview 41 Table 59: Swept Laser Integrated OEM OCT Ophthalmic OCT System - Product Status 42 Table 60: Swept Laser Integrated OEM OCT Ophthalmic OCT System - Product Description 42 Table 61: Glossary 48 1.2 List of Figures Figure 1: Optical Coherence Tomography (OCT) - Pipeline Products by Stage of Development 7 Figure 2: Optical Coherence Tomography (OCT) - Pipeline Products by Territory 8 Figure 3: Optical Coherence Tomography (OCT) - Pipeline Products by Regulatory Path 9 Figure 4: Optical Coherence Tomography (OCT) - Pipeline Products by Estimated Approval Date 10 Figure 5: Optical Coherence Tomography (OCT) - Ongoing Clinical Trials 11

Canon U.S.A., Inc. Cleveland Clinic Hospital Compact Imaging Inc. Duke University George Washington University Heidelberg Engineering GmbH Leica Microsystems GmbH OptoQuest Optos Plc Sinoora Inc. University of California, Berkeley University of Rochester Volcano Corporation