1 Table of Contents 1 Table of Contents 2 1.1 List of Tables 3 1.2 List of Figures 4 2 Introduction 5 2.1 Implantable Remote Patient Monitoring Devices Overview 5 3 Products under Development 6 3.1 Implantable Remote Patient Monitoring Devices - Pipeline Products by Stage of Development 6 3.2 Implantable Remote Patient Monitoring Devices - Pipeline Products by Territory 7 3.3 Implantable Remote Patient Monitoring Devices - Pipeline Products by Regulatory Path 8 3.4 Implantable Remote Patient Monitoring Devices - Pipeline Products by Estimated Approval Date 9 4 Implantable Remote Patient Monitoring Devices - Pipeline Products under Development by Companies 10 4.1 Implantable Remote Patient Monitoring Devices Companies - Pipeline Products by Stage of Development 10 4.2 Implantable Remote Patient Monitoring Devices - Pipeline Products by Stage of Development 11 5 Implantable Remote Patient Monitoring Devices Companies and Product Overview 12 5.1 Boston Scientific Corporation Company Overview 12 5.1.1 Boston Scientific Corporation Pipeline Products & Ongoing Clinical Trials Overview 12 5.2 Endotronix, Inc. Company Overview 14 5.2.1 Endotronix, Inc. Pipeline Products & Ongoing Clinical Trials Overview 14 5.3 Integrated Sensing Systems, Inc. Company Overview 16 5.3.1 Integrated Sensing Systems, Inc. Pipeline Products & Ongoing Clinical Trials Overview 16 5.4 Ludwig Maximilians Universitat Munich Company Overview 22 5.4.1 Ludwig Maximilians Universitat Munich Pipeline Products & Ongoing Clinical Trials Overview 22 5.5 NeuroVista Corporation Company Overview 24 5.5.1 NeuroVista Corporation Pipeline Products & Ongoing Clinical Trials Overview 24 5.6 St. Jude Medical, Inc. Company Overview 26 5.6.1 St. Jude Medical, Inc. Pipeline Products & Ongoing Clinical Trials Overview 26 5.7 Toumaz Technology Limited Company Overview 28 5.7.1 Toumaz Technology Limited Pipeline Products & Ongoing Clinical Trials Overview 28 5.8 Vectorious Medical Technologies Ltd Company Overview 30 5.8.1 Vectorious Medical Technologies Ltd Pipeline Products & Ongoing Clinical Trials Overview 30 6 Implantable Remote Patient Monitoring Devices- Recent Developments 32 6.1 Apr 19, 2016: SHL announces change of Board Member 32 6.2 Mar 18, 2016: SHL provides preliminary update on financial results 2015 32 6.3 Aug 11, 2015: SwedishAmerican First in Rockford to Offer Patients New Heart Failure Monitoring Solution 33 6.4 Jun 24, 2015: St. Jude Medical CardioMEMS HF System Showcased at Premier 2015 ‘Innovation Celebration’ Breakthroughs Conference 33 6.5 May 28, 2015: SHL Telemedicine Reports First Quarter 2015 Financial Results 34 6.6 May 15, 2015: St Jude Releases New Data On CardioMEMS HF System 36 7 Appendix 37 7.1 Methodology 37 7.2 About GlobalData 39 7.3 Contact Us 40 7.4 Disclaimer 40

1.1 List of Tables Table 1: Implantable Remote Patient Monitoring Devices - Pipeline Products by Stage of Development 6 Table 2: Implantable Remote Patient Monitoring Devices - Pipeline Products by Territory 7 Table 3: Implantable Remote Patient Monitoring Devices - Pipeline Products by Regulatory Path 8 Table 4: Implantable Remote Patient Monitoring Devices - Pipeline Products by Estimated Approval Date 9 Table 5: Implantable Remote Patient Monitoring Devices Companies - Pipeline Products by Stage of Development 10 Table 6: Implantable Remote Patient Monitoring Devices - Pipeline Products by Stage of Development 11 Table 7: Boston Scientific Corporation Pipeline Products & Ongoing Clinical Trials Overview 12 Table 8: Remon ImPressure - Product Status 13 Table 9: Remon ImPressure - Product Description 13 Table 10: Endotronix, Inc. Pipeline Products & Ongoing Clinical Trials Overview 14 Table 11: Congestive Heart Failure Monitor - Product Status 15 Table 12: Congestive Heart Failure Monitor - Product Description 15 Table 13: Integrated Sensing Systems, Inc. Pipeline Products & Ongoing Clinical Trials Overview 16 Table 14: Titan Wireless Implantable Hemodynamic Monitor - Pediatrics - Product Status 17 Table 15: Titan Wireless Implantable Hemodynamic Monitor - Pediatrics - Product Description 17 Table 16: Titan Wireless Implantable Hemodynamic Monitor - Planned Surgery - Product Status 18 Table 17: Titan Wireless Implantable Hemodynamic Monitor - Planned Surgery - Product Description 19 Table 18: Titan Wireless Implantable Hemodynamic Monitor - Stand-Alone Procedures - Product Status 20 Table 19: Titan Wireless Implantable Hemodynamic Monitor - Stand-Alone Procedures - Product Description 21 Table 20: Ludwig Maximilians Universitat Munich Pipeline Products & Ongoing Clinical Trials Overview 22 Table 21: IntelliTuM - Product Status 23 Table 22: IntelliTuM - Product Description 23 Table 23: NeuroVista Corporation Pipeline Products & Ongoing Clinical Trials Overview 24 Table 24: NeuroVista Seizure Advisory System - Product Status 25 Table 25: NeuroVista Seizure Advisory System - Product Description 25 Table 26: St. Jude Medical, Inc. Pipeline Products & Ongoing Clinical Trials Overview 26 Table 27: Remote Monitoring Device - Product Status 27 Table 28: Remote Monitoring Device - Product Description 27 Table 29: Toumaz Technology Limited Pipeline Products & Ongoing Clinical Trials Overview 28 Table 30: Implantable Blood Pressure Sensor - Product Status 29 Table 31: Implantable Blood Pressure Sensor - Product Description 29 Table 32: Vectorious Medical Technologies Ltd Pipeline Products & Ongoing Clinical Trials Overview 30 Table 33: Intra-Cardiac Hemodynamic Indication System - Asymptomatic Patients - Product Status 31 Table 34: Intra-Cardiac Hemodynamic Indication System - Asymptomatic Patients - Product Description 31 Table 35: Glossary 38 1.2 List of Figures Figure 1: Implantable Remote Patient Monitoring Devices - Pipeline Products by Stage of Development 6 Figure 2: Implantable Remote Patient Monitoring Devices - Pipeline Products by Territory 7 Figure 3: Implantable Remote Patient Monitoring Devices - Pipeline Products by Regulatory Path 8 Figure 4: Implantable Remote Patient Monitoring Devices - Pipeline Products by Estimated Approval Date 9

Boston Scientific Corporation Endotronix, Inc. Integrated Sensing Systems, Inc. Ludwig Maximilians Universitat Munich NeuroVista Corporation St. Jude Medical, Inc. Toumaz Technology Limited Vectorious Medical Technologies Ltd