1 Table of Contents 1 Table of Contents 2 1.1 List of Tables 4 1.2 List of Figures 5 2 Introduction 6 2.1 What Is This Report About? 6 2.2 Interventional Cardiology Devices Market Segmentation 6 2.3 Definitions of Markets Covered in the Report 7 3 Interventional Cardiology Market, Canada 11 3.1 Interventional Cardiology Market, Canada, Revenue ($m), 2007-2014 11 3.2 Interventional Cardiology Market, Canada, Revenue ($m), 2014-2021 13 3.2.1 Arteriotomy Closure Devices Market, Canada, Revenue ($m), by Segment, 2007-2014 15 3.2.2 Cardiac Catheters Market, Canada, Revenue ($m), by Segment, 2007-2014 17 3.2.3 Coronary Stents Market, Canada, Revenue ($m), by Segment, 2007-2014 19 3.2.4 Intravascular Ultrasound Systems (IVUS) Market, Canada, Revenue ($m), by Segment, 2007-2014 21 3.2.5 PTCA Balloons Market, Canada, Revenue ($m), by Segment, 2007-2014 23 3.2.6 Arteriotomy Closure Devices Market, Canada, Revenue ($m), by Segment, 2014-2021 25 3.2.7 Cardiac Catheters Market, Canada, Revenue ($m), by Segment, 2014-2021 27 3.2.8 Coronary Stents Market, Canada, Revenue ($m), by Segment, 2014-2021 29 3.2.9 Intravascular Ultrasound Systems (IVUS) Market, Canada, Revenue ($m), by Segment, 2014-2021 31 3.2.10 PTCA Balloons Market, Canada, Revenue ($m), by Segment, 2014-2021 33 3.3 Interventional Cardiology Market, Canada, Volume (Units), 2007-2014 35 3.4 Interventional Cardiology Market, Canada, Volume (Units), 2014-2021 37 3.4.1 Arteriotomy Closure Devices Market, Canada, Volume (Units), by Segment, 2007-2014 39 3.4.2 Cardiac Catheters Market, Canada, Volume (Units), by Segment, 2007-2014 41 3.4.3 Coronary Stents Market, Canada, Volume (Units), by Segment, 2007-2014 43 3.4.4 Intravascular Ultrasound Systems (IVUS) Market, Canada, Volume (Units), by Segment, 2007-2014 45 3.4.5 PTCA Balloons Market, Canada, Volume (Units), by Segment, 2007-2014 47 3.4.6 Arteriotomy Closure Devices Market, Canada, Volume (Units), by Segment, 2014-2021 49 3.4.7 Cardiac Catheters Market, Canada, Volume (Units), by Segment, 2014-2021 51 3.4.8 Coronary Stents Market, Canada, Volume (Units), by Segment, 2014-2021 53 3.4.9 Intravascular Ultrasound Systems (IVUS) Market, Canada, Volume (Units), by Segment, 2014-2021 55 3.4.10 PTCA Balloons Market, Canada, Volume (Units), by Segment, 2014-2021 57 3.5 Interventional Cardiology Market, Canada, Average Price ($), 2007-2021 59 3.6 Interventional Cardiology Market, Canada, Distribution Share by Revenue ($m), 2013-2014 63 3.7 Interventional Cardiology Market, Canada, Company Share by Revenue ($m), 2014 64 4 Overview of Key Companies in Canada, Interventional Cardiology Market 66 4.1 Boston Scientific Corporation 66 4.1.1 Company Overview 66 4.2 Abbott Laboratories 66 4.2.1 Company Overview 66 4.3 Medtronic plc 66 4.3.1 Company Overview 66 4.4 Biotronik SE & Co. KG 67 4.4.1 Company Overview 67 4.5 OrbusNeich 67 4.5.1 Company Overview 67 4.6 Terumo Corporation 67 4.6.1 Company Overview 67 4.7 St. Jude Medical, Inc. 67 4.7.1 Company Overview 67 4.8 Edwards Lifesciences Corporation 68 4.8.1 Company Overview 68 4.9 Cordis Corporation 68 4.9.1 Company Overview 68 4.10 Asahi Intecc Co., Ltd. 68 4.10.1 Company Overview 68 4.11 Cook Medical Incorporated 68 4.11.1 Company Overview 68 4.12 Volcano Corporation 69 4.12.1 Company Overview 69 5 Interventional Cardiology Market Pipeline Products 70 6 Financial Deals Landscape 72 6.1 Equity Offerings 72 6.1.1 Neovasc Raises USD75 Million in Public Offering of Shares 72 7 Recent Developments 74 7.1 Corporate Communications 74 7.1.1 May 26, 2015: IMRIS and Two Subsidiaries File for Chapter 11 Protection 74 7.2 Financial Announcements 74 7.2.1 Nov 09, 2015: Neovasc Reports Results for the Third Quarter of 2015 74 7.2.2 Aug 06, 2015: Neovasc Reports Results for the Second Quarter of 2015 78 7.2.3 Jul 01, 2015: Aesculap Implant Systems Introduces the Modulift Vertebral Body Replacement System 81 7.2.4 May 12, 2015: Neovasc Reports Results for the First Quarter of 2015 83 7.2.5 Mar 30, 2015: Neovasc Announces Results for the Fourth Quarter and Full Year Ended 2014 85 8 Appendix 89 8.1 Research Methodology 90 8.1.1 Coverage 90 8.1.2 Secondary Research 90 8.1.3 Primary Research 91 8.1.4 Market Modeling and Forecasting 92 8.1.5 Company Share Analysis 95 8.1.6 Distribution Share Analysis 96 8.2 Expert Panel 97 8.3 GlobalData Consulting 97 8.4 Contact Us 97 8.5 Disclaimer 97

1.1 List of Tables Table 1: Interventional Cardiology Market, Canada, Revenue ($m), USD Constant, Historic, 2007-2014 12 Table 2: Interventional Cardiology Market, Canada, Revenue ($m), USD Constant, Forecast, 2014-2021 14 Table 3: Arteriotomy Closure Devices Market, Canada, Revenue ($m), USD Constant, Historic, 2007-2014 16 Table 4: Cardiac Catheters Market, Canada, Revenue ($m), USD Constant, Historic, 2007-2014 18 Table 5: Coronary Stents Market, Canada, Revenue ($m), USD Constant, Historic, 2007-2014 20 Table 6: Intravascular Ultrasound Systems (IVUS) Market, Canada, Revenue ($m), USD Constant, Historic, 2007-2014 22 Table 7: PTCA Balloons Market, Canada, Revenue ($m), USD Constant, Historic, 2007-2014 24 Table 8: Arteriotomy Closure Devices Market, Canada, Revenue ($m), USD Constant, Forecast, 2014-2021 26 Table 9: Cardiac Catheters Market, Canada, Revenue ($m), USD Constant, Forecast, 2014-2021 28 Table 10: Coronary Stents Market, Canada, Revenue ($m), USD Constant, Forecast, 2014-2021 30 Table 11: Intravascular Ultrasound Systems (IVUS) Market, Canada, Revenue ($m), USD Constant, Forecast, 2014-2021 32 Table 12: PTCA Balloons Market, Canada, Revenue ($m), USD Constant, Forecast, 2014-2021 34 Table 13: Interventional Cardiology Market, Canada, Volume (Units), Historic, 2007-2014 36 Table 14: Interventional Cardiology Market, Canada, Volume (Units), Forecast, 2014-2021 38 Table 15: Arteriotomy Closure Devices Market, Canada, Volume (Units), Historic, 2007-2014 40 Table 16: Cardiac Catheters Market, Canada, Volume (Units), Historic, 2007-2014 42 Table 17: Coronary Stents Market, Canada, Volume (Units), Historic, 2007-2014 44 Table 18: Intravascular Ultrasound Systems (IVUS) Market, Canada, Volume (Units), Historic, 2007-2014 46 Table 19: PTCA Balloons Market, Canada, Volume (Units), Historic, 2007-2014 48 Table 20: Arteriotomy Closure Devices Market, Canada, Volume (Units), Forecast, 2014-2021 50 Table 21: Cardiac Catheters Market, Canada, Volume (Units), Forecast, 2014-2021 52 Table 22: Coronary Stents Market, Canada, Volume (Units), Forecast, 2014-2021 54 Table 23: Intravascular Ultrasound Systems (IVUS) Market, Canada, Volume (Units), Forecast, 2014-2021 56 Table 24: PTCA Balloons Market, Canada, Volume (Units), Forecast, 2014-2021 58 Table 25: Interventional Cardiology Market, Canada, Average Price ($) Historic, 2007-2014 59 Table 26: Interventional Cardiology Market, Canada, Average Price ($), Forecast, 2014-2021 61 Table 27: Interventional Cardiology Market, Canada, Distribution Share by Revenue ($m), USD Constant, 2013-2014 63 Table 28: Interventional Cardiology Market, Canada, Company Share by Revenue ($m), USD Constant, 2014 65 Table 29: Interventional Cardiology Market Pipeline Products 70 Table 30: Neovasc Raises USD75 Million in Public Offering of Shares 72 Table 31: Total Number of Primary Research Participants, Cardiovascular Devices Market, by Country 92 1.2 List of Figures Figure 1: Interventional Cardiology Market, Canada, Revenue ($m), USD Constant, Historic, 2007-2014 11 Figure 2: Interventional Cardiology Market, Canada, Revenue ($m), USD Constant, Forecast, 2014-2021 13 Figure 3: Arteriotomy Closure Devices Market, Canada, Revenue ($m), USD Constant, Historic, 2007-2014 15 Figure 4: Cardiac Catheters Market, Canada, Revenue ($m), USD Constant, Historic, 2007-2014 17 Figure 5: Coronary Stents Market, Canada, Revenue ($m), USD Constant, Historic, 2007-2014 19 Figure 6: Intravascular Ultrasound Systems (IVUS) Market, Canada, Revenue ($m), USD Constant, Historic, 2007-2014 21 Figure 7: PTCA Balloons Market, Canada, Revenue ($m), USD Constant, Historic, 2007-2014 23 Figure 8: Arteriotomy Closure Devices Market, Canada, Revenue ($m), USD Constant, Forecast, 2014-2021 25 Figure 9: Cardiac Catheters Market, Canada, Revenue ($m), USD Constant, Forecast, 2014-2021 27 Figure 10: Coronary Stents Market, Canada, Revenue ($m), USD Constant, Forecast, 2014-2021 29 Figure 11: Intravascular Ultrasound Systems (IVUS) Market, Canada, Revenue ($m), USD Constant, Forecast, 2014-2021 31 Figure 12: PTCA Balloons Market, Canada, Revenue ($m), USD Constant, Forecast, 2014-2021 33 Figure 13: Interventional Cardiology Market, Canada, Volume (Units), Historic, 2007-2014 35 Figure 14: Interventional Cardiology Market, Canada, Volume (Units), Forecast, 2014-2021 37 Figure 15: Arteriotomy Closure Devices Market, Canada, Volume (Units), Historic, 2007-2014 39 Figure 16: Cardiac Catheters Market, Canada, Volume (Units), Historic, 2007-2014 41 Figure 17: Coronary Stents Market, Canada, Volume (Units), Historic, 2007-2014 43 Figure 18: Intravascular Ultrasound Systems (IVUS) Market, Canada, Volume (Units), Historic, 2007-2014 45 Figure 19: PTCA Balloons Market, Canada, Volume (Units), Historic, 2007-2014 47 Figure 20: Arteriotomy Closure Devices Market, Canada, Volume (Units), Forecast, 2014-2021 49 Figure 21: Cardiac Catheters Market, Canada, Volume (Units), Forecast, 2014-2021 51 Figure 22: Coronary Stents Market, Canada, Volume (Units), Forecast, 2014-2021 53 Figure 23: Intravascular Ultrasound Systems (IVUS) Market, Canada, Volume (Units), Forecast, 2014-2021 55 Figure 24: PTCA Balloons Market, Canada, Volume (Units), Forecast, 2014-2021 57 Figure 25: Interventional Cardiology Market, Canada, Company Share (%) 2014 64 Figure 26: GlobalData Epidemiology-Based Forecasting Model 94 Figure 27: GlobalData Capital Equipment-Based Forecasting Model 95 Figure 28: Primary Interviews by Participant Type (%) 96

Boston Scientific Corporation Abbott Laboratories Medtronic plc Biotronik SE & Co. KG OrbusNeich Terumo Corporation St. Jude Medical, Inc. Edwards Lifesciences Corporation Cordis Corporation Asahi Intecc Co., Ltd. Cook Medical Incorporated Volcano Corporation