1 Table of Contents 1 Table of Contents 2 1.1 List of Tables 4 1.2 List of Figures 5 2 Introduction 6 2.1 What Is This Report About? 6 2.2 Prosthetic Heart Valves Market Segmentation 6 2.3 Definitions of Markets Covered in the Report 7 3 Prosthetic Heart Valves Market, Japan 8 3.1 Prosthetic Heart Valves Market, Japan, Revenue ($m), 2007-2014 8 3.2 Prosthetic Heart Valves Market, Japan, Revenue ($m), 2014-2021 10 3.2.1 Mechanical Heart Valves Market, Japan, Revenue ($m), by Segment, 2007-2014 12 3.2.2 Tissue Heart Valves Market, Japan, Revenue ($m), by Segment, 2007-2014 14 3.2.3 Transcatheter Heart Valves Market, Japan, Revenue ($m), by Segment, 2007-2014 16 3.2.4 Mechanical Heart Valves Market, Japan, Revenue ($m), by Segment, 2014-2021 17 3.2.5 Tissue Heart Valves Market, Japan, Revenue ($m), by Segment, 2014-2021 19 3.2.6 Transcatheter Heart Valves Market, Japan, Revenue ($m), by Segment, 2014-2021 21 3.3 Prosthetic Heart Valves Market, Japan, Volume (Units), 2007-2014 23 3.4 Prosthetic Heart Valves Market, Japan, Volume (Units), 2014-2021 25 3.4.1 Mechanical Heart Valves Market, Japan, Volume (Units), by Segment, 2007-2014 27 3.4.2 Tissue Heart Valves Market, Japan, Volume (Units), by Segment, 2007-2014 29 3.4.3 Transcatheter Heart Valves Market, Japan, Volume (Units), by Segment, 2007-2014 31 3.4.4 Mechanical Heart Valves Market, Japan, Volume (Units), by Segment, 2014-2021 32 3.4.5 Tissue Heart Valves Market, Japan, Volume (Units), by Segment, 2014-2021 34 3.4.6 Transcatheter Heart Valves Market, Japan, Volume (Units), by Segment, 2014-2021 36 3.5 Prosthetic Heart Valves Market, Japan, Average Price ($), 2007-2021 38 3.6 Prosthetic Heart Valves Market, Japan, Distribution Share by Revenue ($m), 2013-2014 40 3.7 Prosthetic Heart Valves Market, Japan, Company Share by Revenue ($m), 2014 41 4 Overview of Key Companies in Japan, Prosthetic Heart Valves Market 43 4.1 Edwards Lifesciences Corporation 43 4.1.1 Company Overview 43 4.2 Medtronic plc 43 4.2.1 Company Overview 43 4.3 St. Jude Medical, Inc. 43 4.3.1 Company Overview 43 4.4 Sorin S.p.A. (Inactive) 44 4.4.1 Company Overview 44 4.5 Lepu Medical Technology (Beijing) Co., Ltd. 44 4.5.1 Company Overview 44 5 Prosthetic Heart Valves Market Pipeline Products 45 6 Recent Developments 46 6.1 Other Significant Developments 46 6.1.1 May 27, 2015: Novocure Announces Commercial Launch of Optune (the NovoTTF-100A System) in Japan 46 7 Appendix 47 7.1 Research Methodology 48 7.1.1 Coverage 48 7.1.2 Secondary Research 48 7.1.3 Primary Research 49 7.1.4 Market Modeling and Forecasting 50 7.1.5 Company Share Analysis 53 7.1.6 Distribution Share Analysis 54 7.2 Expert Panel 55 7.3 GlobalData Consulting 55 7.4 Contact Us 55 7.5 Disclaimer 55

1.1 List of Tables Table 1: Prosthetic Heart Valves Market, Japan, Revenue ($m), USD Constant, Historic, 2007-2014 9 Table 2: Prosthetic Heart Valves Market, Japan, Revenue ($m), USD Constant, Forecast, 2014-2021 11 Table 3: Mechanical Heart Valves Market, Japan, Revenue ($m), USD Constant, Historic, 2007-2014 13 Table 4: Tissue Heart Valves Market, Japan, Revenue ($m), USD Constant, Historic, 2007-2014 15 Table 5: Transcatheter Heart Valves Market, Japan, Revenue ($m), USD Constant, Historic, 2007-2014 16 Table 6: Mechanical Heart Valves Market, Japan, Revenue ($m), USD Constant, Forecast, 2014-2021 18 Table 7: Tissue Heart Valves Market, Japan, Revenue ($m), USD Constant, Forecast, 2014-2021 20 Table 8: Transcatheter Heart Valves Market, Japan, Revenue ($m), USD Constant, Forecast, 2014-2021 22 Table 9: Prosthetic Heart Valves Market, Japan, Volume (Units), Historic, 2007-2014 24 Table 10: Prosthetic Heart Valves Market, Japan, Volume (Units), Forecast, 2014-2021 26 Table 11: Mechanical Heart Valves Market, Japan, Volume (Units), Historic, 2007-2014 28 Table 12: Tissue Heart Valves Market, Japan, Volume (Units), Historic, 2007-2014 30 Table 13: Transcatheter Heart Valves Market, Japan, Volume (Units), Historic, 2007-2014 31 Table 14: Mechanical Heart Valves Market, Japan, Volume (Units), Forecast, 2014-2021 33 Table 15: Tissue Heart Valves Market, Japan, Volume (Units), Forecast, 2014-2021 35 Table 16: Transcatheter Heart Valves Market, Japan, Volume (Units), Forecast, 2014-2021 37 Table 17: Prosthetic Heart Valves Market, Japan, Average Price ($) Historic, 2007-2014 38 Table 18: Prosthetic Heart Valves Market, Japan, Average Price ($), Forecast, 2014-2021 39 Table 19: Prosthetic Heart Valves Market, Japan, Distribution Share by Revenue ($m), USD Constant, 2013-2014 40 Table 20: Prosthetic Heart Valves Market, Japan, Company Share by Revenue ($m), USD Constant, 2014 42 Table 21: Prosthetic Heart Valves Market Pipeline Products 45 Table 22: Total Number of Primary Research Participants, Cardiovascular Devices Market, by Country 50 1.2 List of Figures Figure 1: Prosthetic Heart Valves Market, Japan, Revenue ($m), USD Constant, Historic, 2007-2014 8 Figure 2: Prosthetic Heart Valves Market, Japan, Revenue ($m), USD Constant, Forecast, 2014-2021 10 Figure 3: Mechanical Heart Valves Market, Japan, Revenue ($m), USD Constant, Historic, 2007-2014 12 Figure 4: Tissue Heart Valves Market, Japan, Revenue ($m), USD Constant, Historic, 2007-2014 14 Figure 5: Transcatheter Heart Valves Market, Japan, Revenue ($m), USD Constant, Historic, 2007-2014 16 Figure 6: Mechanical Heart Valves Market, Japan, Revenue ($m), USD Constant, Forecast, 2014-2021 17 Figure 7: Tissue Heart Valves Market, Japan, Revenue ($m), USD Constant, Forecast, 2014-2021 19 Figure 8: Transcatheter Heart Valves Market, Japan, Revenue ($m), USD Constant, Forecast, 2014-2021 21 Figure 9: Prosthetic Heart Valves Market, Japan, Volume (Units), Historic, 2007-2014 23 Figure 10: Prosthetic Heart Valves Market, Japan, Volume (Units), Forecast, 2014-2021 25 Figure 11: Mechanical Heart Valves Market, Japan, Volume (Units), Historic, 2007-2014 27 Figure 12: Tissue Heart Valves Market, Japan, Volume (Units), Historic, 2007-2014 29 Figure 13: Transcatheter Heart Valves Market, Japan, Volume (Units), Historic, 2007-2014 31 Figure 14: Mechanical Heart Valves Market, Japan, Volume (Units), Forecast, 2014-2021 32 Figure 15: Tissue Heart Valves Market, Japan, Volume (Units), Forecast, 2014-2021 34 Figure 16: Transcatheter Heart Valves Market, Japan, Volume (Units), Forecast, 2014-2021 36 Figure 17: Prosthetic Heart Valves Market, Japan, Company Share (%) 2014 41 Figure 18: GlobalData Epidemiology-Based Forecasting Model 52 Figure 19: GlobalData Capital Equipment-Based Forecasting Model 53 Figure 20: Primary Interviews by Participant Type (%) 54

Edwards Lifesciences Corporation Medtronic plc St. Jude Medical, Inc. Sorin S.p.A. Lepu Medical Technology (Beijing) Co., Ltd.