Table Of Contents
Introduction
Overview: Substance Abuse, Deterrence and Treatments
Contributing Factors of Drug Abuse and Addiction
Commonly Abused Substances
Prescription or OTC Substance Abuse
Common Effects and Symptoms of Substance Abuse
Substance Abuse and Brain Function
Health, Social and Economic Impact of Substance Abuse
Impact of Substance Abuse on Specific Population Groups
Substance Abuse: Global Trends and Regulatory Developments
Illicit Substance Abuse: Global Trends
Trends in Global Number of Abusers of Illicit Drugs
Global Trends in Alcohol and Nicotine Use and Addiction
Global Trends in Injecting Drug Use and HIV Infection
International Guidelines Developed by the UN for Abusable Substances
The Role of the International Narcotics Control Board in Controlling Substance Abuse
Worldwide Differences in Regulations and Approaches to Tackle Substance Abuse
Unmet Medical Need Analysis and Gaps in the Treatment of Substance abuse
Technologies for Developing Abuse Deterrent Products
Abuse Deterrent Formulation Technologies: Key Advantages
Limitations of Abuse Deterrent Formulations and Arguments Against Adoption
Abuse Deterrent Formulation Strategies
Case Studies
Embeda
Suboxone
INTAC technology
DETERx technology
Osmotic extended-release oral delivery system
Aversion Technology
iCRT-deter
Prodrug Combined with MPAR Technology
Marketed Products For the Treatment of Substance Abuse
Marketed Therapies by Type of Addiction
Volume of Companies Operating in the Substance Abuse Treatment Market by Type of Addiction
Substance Abuse Therapies with Highest Degree of Commercialization
Companies with Highest Volume of Marketed Therapies for Substance Abuse
Key Companies with a Wide Global Presence
Competitive and Product Landscape Analysis in Key Countries
Lists of Key Marketed Products by Type of Addiction
Key Routes of Administration of Marketed Products by Type of Addiction
Pipeline Products For the Treatment of Substance Abuse
Volume of Pipeline Therapies by Type of Organization
Volume of Pipeline Therapies by Type of Addiction
Organizations with the Highest Volume of Pipeline Therapies
Volume of Pipeline Therapies by Stage of Development
Profiles of Late Stage Pipeline Products
Volume of Pipeline Therapies by Type of Molecule and Route of Administration
Future Treatment Landscape
Bibliography